Additional file 16 of Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides

Additional file 16. Structure of genes encoding precursors of candidate ligands for kisspeptin-type receptors in other echinoderms. Comparison of the exon/intron structure of genes encoding precursors of candidate ligands for kisspeptin-type receptors in echinoderms and genes encoding kisspeptin-type precursors in three vertebrate species. Exons are shown as rectangles, with non-coding regions white and protein-coding regions black or colored (regions of exons encoding the N-terminal signal peptide, neuropeptides and predicted monobasic or dibasic cleavage sites are shown in blue, red, and green, respectively). Introns are shown as lines, with intron length (bases) stated underneath and intron phase stated above. Species names are abbreviated as follows: Acanthaster planci, Ap; Strongylocentrotus purpuratus, Sp; Apostichopus japonicus, Aj. The accession numbers for the sequences of the precursors shown in this figure are listed in additional file 17.