Additional file 7. CLuster Analysis of Sequences (CLANS) of receptors identified by BLAST analysis of bilaterian proteomes using human and S. purpuratus kisspeptin-type receptors as queries. BLOSUM62 cluster map shows kisspeptin-type receptors, the closely related galanin/allatostatin-A-type receptors, and other neuropeptide receptor families: allatotropin/orexin, neuropeptide Y, tachykinin, somatostatin/allatostatin-C, CCHamide/gastrin-releasing peptide. Nodes are labelled with taxon-specific shapes and colors, as shown in the key. Connections represent BLAST relationships with a P value > 1e-40. All family names of receptors are labelled in the figure. The accession numbers for the receptors shown in this figure are provided in additional file 2.
|Date made available||2022|