20062019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2019

Pathological Changes to the Subcortical Visual System and its Relationship to Visual Hallucinations in Dementia with Lewy Bodies

Erskine, D., Taylor, J-P., Thomas, A., Collerton, D., McKeith, I., Khundakar, A., Attems, J. & Morris, C., 6 Feb 2019, In : Neuroscience Bulletin. 35, 2, p. 295-300 6 p.

Research output: Contribution to journalArticle

Open Access
File
47 Downloads (Pure)

Trichloroethylene and its metabolite TaClo lead to degeneration of substantia nigra dopaminergic neurones: Effects in wild type and human A30P mutant α-synuclein mice

Keane, P. C., Hanson, P. S., Patterson, L., Blain, P. G., Khundakar, A. A., Judge, S. J., Kahle, P. J. & Morris, C. M., 15 Oct 2019, In : Neuroscience Letters. 711, 6 p., 134437.

Research output: Contribution to journalArticle

Open Access
File
110 Downloads (Pure)
2018

Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology?

Unger, M. S., Marschallinger, J., Kaindl, J., Klein, B., Johnson, M., Khundakar, A., Roßner, S., Heneka, M. T., Couillard-Despres, S., Rockenstein, E., Masliah, E., Attems, J. & Aigner, L., 31 Aug 2018, In : Alzheimer's and Dementia. 14, 8, p. 1022-1037 16 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
157 Downloads (Pure)

Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies

Erskine, D., Ding, J., Thomas, A. J., Kaganovich, A., Khundakar, A., Hanson, P. S., Taylor, JP., McKeith, I. G., Attems, J., Cookson, M. R. & Morris, C., 23 Mar 2018, In : Movement Disorders : official journal of the Movement Disorder Society. 33, 6, p. 982-991 10 p.

Research output: Contribution to journalArticle

Open Access
File
149 Downloads (Pure)
2017

Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies

Erskine, D., Thomas, A. J., Taylor, J. P., Savage, M. A., Attems, J., McKeith, I. G., Morris, C. M. & Khundakar, A., 1 Jun 2017, In : American Journal of Geriatric Psychiatry. 25, 6, p. 595-604 10 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
161 Downloads (Pure)

Quantitative neuropathology: an update on automated methodologies and implications for large scale cohorts

Walker, L., McAleese, K. E., Johnson, M., Khundakar, A., Erskine, D., Thomas, A. J., McKeith, I. G. & Attems, J., 30 Jun 2017, In : Journal of Neural Transmission. 124, 6, p. 671-683 13 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
143 Downloads (Pure)

Specific patterns of neuronal loss in the pulvinar nucleus in dementia with lewy bodies

Erskine, D., Thomas, A. J., Attems, J., Taylor, J. P., McKeith, I. G., Morris, C. M. & Khundakar, A., 1 Mar 2017, In : Movement Disorders. 32, 3, p. 414-422 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
157 Downloads (Pure)
2016

Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations

Khundakar, A., Hanson, P. S., Erskine, D., Lax, N. Z., Roscamp, J., Karyka, E., Tsefou, E., Singh, P., Cockell, S. J., Gribben, A., Ramsay, L., Blain, P. G., Mosimann, U. P., Lett, D. J., Elstner, M., Turnbull, D. M., Xiang, C. C., Brownstein, M. J., O'Brien, J. T., Taylor, J. P. & 4 others, Attems, J., Thomas, A. J., McKeith, I. G. & Morris, C. M., 1 Jan 2016, In : Acta neuropathologica communications. 4, 1, 66.

Research output: Contribution to journalArticle

File
14 Citations (Scopus)
117 Downloads (Pure)

Changes to the lateral geniculate nucleus in Alzheimer's disease but not dementia with Lewy bodies

Erskine, D., Taylor, J. P., Firbank, M. J., Patterson, L., Onofrj, M., O'Brien, J. T., Mckeith, I. G., Attems, J., Thomas, A. J., Morris, C. M. & Khundakar, A., 1 Jun 2016, In : Neuropathology and Applied Neurobiology. 42, 4, p. 366-376 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Stereological approaches to dementia research using human brain tissue

Erskine, D. & Khundakar, A., 1 Oct 2016, In : Journal of Chemical Neuroanatomy. 76, p. 73-81 9 p.

Research output: Contribution to journalArticle

File
2 Citations (Scopus)
119 Downloads (Pure)
2015

Neuropathology of depression in Alzheimer's disease: Current knowledge and the potential for new treatments

Khundakar, A. A. & Thomas, A. J., 1 Jan 2015, Handbook of Depression in Alzheimer's Disease. Smith, G. S. (ed.). IOS Press, p. 187-201 15 p. (Advances in Alzheimer's Disease; vol. 4).

Research output: Chapter in Book/Report/Conference proceedingChapter

File
92 Downloads (Pure)

Neuropathology of depression in Alzheimer's disease: Current knowledge and the potential for new treatments

Khundakar, A. A. & Thomas, A. J., 1 Jan 2015, In : Journal of Alzheimer's Disease. 44, 1, p. 27-41 15 p.

Research output: Contribution to journalReview article

28 Citations (Scopus)
2014

Cellular morphometry in late-life depression: A review of postmortem studies

Khundakar, A. & Thomas, A. J., 1 Jan 2014, In : American Journal of Geriatric Psychiatry. 22, 2, p. 122-132 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Morphometry of the hippocampal microvasculature in post-stroke and age-related dementias

Burke, M. J. C., Nelson, L., Slade, J. Y., Oakley, A. E., Khundakar, A. & Kalaria, R. N., 1 Jan 2014, In : Neuropathology and Applied Neurobiology. 40, 3, p. 284-295 12 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
126 Downloads (Pure)

Neuron volumes in hippocampal subfields in delayed poststroke and aging-related dementias

Gemmell, E., Tam, E., Allan, L., Hall, R., Khundakar, A., Oakley, A. E., Thomas, A., Deramecourt, V. & Kalaria, R. N., 1 Jan 2014, In : Journal of Neuropathology and Experimental Neurology. 73, 4, p. 305-311 7 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
139 Downloads (Pure)

Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias

Foster, V., Oakley, A. E., Slade, J. Y., Hall, R., Polvikoski, T. M., Burke, M., Thomas, A. J., Khundakar, A., Allan, L. M. & Kalaria, R. N., 1 Jan 2014, In : Brain. 137, 9, p. 2509-2521 13 p.

Research output: Contribution to journalArticle

File
16 Citations (Scopus)
131 Downloads (Pure)

The role of 5-hydroxytryptamine receptor subtypes in the regulation of brain-derived neurotrophic factor gene expression

Zetterström, T. S. C., Coppell, A. A. & Khundakar, A., 1 Jan 2014, In : Journal of Pharmacy and Pharmacology. 66, 1, p. 53-61 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
78 Downloads (Pure)
2013

Effects of repeated 5-HT6 receptor stimulation on BDNF gene expression and cell survival

de Foubert, G., Khundakar, A. & Zetterström, T. S., 11 Oct 2013, In : Neuroscience Letters. 553, p. 211-215 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The Possible Applications (and Pitfalls!) of Stereological Analysis in Postmortem Brain Research

Khundakar, A. & Thomas, A. J., 25 Nov 2013, Neurostereology: Unbiased Stereology of Neural Systems. Wiley, p. 129-138 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Hippocampal neuronal atrophy and cognitive function in delayed poststroke and aging-related dementias

Gemmell, E., Bosomworth, H., Allan, L., Hall, R., Khundakar, A., Oakley, A. E., Deramecourt, V., Polvikoski, T. M., O'Brien, J. T. & Kalaria, R. N., 1 Mar 2012, In : Stroke. 43, 3, p. 808-814 7 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2011

A morphometric examination of neuronal and glial cell pathology in the orbitofrontal cortex in late-life depression

Khundakar, A., Morris, C., Oakley, A. & Thomas, A. J., 1 Feb 2011, In : International Psychogeriatrics. 23, 1, p. 132-140 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Cellular pathology within the anterior cingulate cortex of patients with late-life depression: A morphometric study

Khundakar, A., Morris, C. M., Oakley, A. E. & Thomas, A. J., 30 Nov 2011, In : Psychiatry Research - Neuroimaging. 194, 2, p. 184-189 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression

Khundakar, A. & Zetterström, T. S. C., 5 Dec 2011, In : European Journal of Pharmacology. 671, 1-3, p. 33-38 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
1 Citation (Scopus)

Morphometric analysis of neuronal and glial cell pathology in the caudate nucleus in late-life depression

Khundakar, A., Morris, C., Oakley, A. & Thomas, A. J., 1 Jan 2011, In : American Journal of Geriatric Psychiatry. 19, 2, p. 132-141 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
11 Citations (Scopus)
2009

Differential regulation of psychostimulant-induced gene expression of brain derived neurotrophic factor and the immediate-early gene Arc in the juvenile and adult brain

Banerjee, P. S., Aston, J., Khundakar, A. & Zetterström, T. S. C., 1 Feb 2009, In : European Journal of Neuroscience. 29, 3, p. 465-476 12 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Morphometric changes in early- and late-life major depressive disorder: Evidence from postmortem studies

Khundakar, A. & Thomas, A. J., 1 Oct 2009, In : International Psychogeriatrics. 21, 5, p. 844-854 11 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)

Morphometry analysis of neuronal and glial cell pathology in the dorsolateral prefrontal cortex in late-life depression

Khundakar, A., Morris, C., Oakley, A., McMeekin, W. & Thomas, A. J., 1 Aug 2009, In : British Journal of Psychiatry. 195, 2, p. 163-169 7 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
2006

Biphasic change in BDNF gene expression following antidepressant drug treatment explained by differential transcript regulation

Khundakar, A. & Zetterström, T. S. C., 23 Aug 2006, In : Brain Research. 1106, 1, p. 12-20 9 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)