Projects per year
Personal profile
Academic Biography
Dr Orr studied a degree in Biotechnology at Northumbria University where she received first class honours and the Avecia prize for Biotechnology. Caroline then went on to gain a PhD in Molecular Biology from Northumbria University, co-funded by Newcastle University. Caroline’s PhD involved using molecular biology techniques to understand bacterial communities residing in agricultural soils and the impacts they may have on the nitrogen cycle. Caroline then completed postdoctoral positions at both Northumbria and Newcastle Universities before taking up a teaching position at Teesside in 2011.
SInce joining Teesside University Caroline has been involved in a range of microbiology based projects working with industrial, environmental, medical and academic collaborators. Caroline is interested in using her skills in analysing and optimising complex communities to understand how microbes can help improve soil health via controlled nutirent cycling, improve industrial processes and the circular economy by utilising diverse waste streams, and to improve health by understanding microbiome interactions.
Summary of Research Interests
Caroline’s expertise and interests include application of microbial ecology theory to a range of diverse environments. Specialising in anaerobic environments, Caroline uses a range of sequencing applications to identify changes in microbial community composition and activity. This information, coupled with studying changes in environmental parameters, gas production and other biotic factors, allows understanding of the impact changing microbial communities have on their environments and vice versa.
Caroline collaborates actively with academics nationally and internationally, as well as local industrial partners. Caroline has published in peer reviewed journals of international quality and is an active member of the Microbiology Society.
Research Projects & External Funding
Caroline works on a range of projects studying microbial communities and their impacts on the environment. Her main background is in environmental microbiology where she is interested in nutrient cycling within agricultural lands and optimising soil health. However, as her expertise extends to many microbiological methods she is involved with other active projects including:
1. Optimisation of Anaerobic Digestion
Caroline collaborates with local industrial partners to investigate microbial processes involved in effective anaerobic digestion processes. This includes identifying potential feedstocks for small scale production and preserving and enhancing complex communities within larger scale established digesters.
2. Microbiomes, the impact of probiotics and fluoride
Caroline is involved in a range of microbiome-based studies including: the impacts of probiotics on health indicators within the preterm infant gut, influence of microbes within chorioamnionitits and the potential role of fluoride in shaping the oral and gut microbiome in vulnerable groups.
3. Microbiology associated with preservation of cultural heritage and the impacts of climate change.
Caroline is collaborating with colleagues within the University, nationally and internationally and working specifically with sites of archaeological interest such as Vindolanda and Magna off Hadrian's Wall. We are specifically interested in firstly understanding preservation and degradation dynamics within complex archaeological sites. Using a range of microbial and chemical parameters we are also interested in monitoring changes at sites of interest to understand how changing climatic conditions can impact below and above ground artefacts and their preservation.
PhD and Research Opportunities
Caroline is always interested to hear from prospective PhD students. She has a wealth of experience in PhD supervision and has successfully completed many students.
Areas which Caroline is interested in PhD supervision include:
- Optimisation of Anaerobic Digestion
- Microbial potential within the circular economy and use of novel waste streams
- Microbial diversity and nutrient cycling within soil environments - particulary with regard to fertiliser and pesticide management
- Microbiomes and the impacts of probiotics
External Roles and Professional Activities
Caroline collaborates with professional bodies, academic socieites and other institutions widely. This includes being elected to the Microbiology Society Impact and Influence Committee and working with Applied Microbiology International on soil health policy.
Caroline is currently external examiner for Liverpool John Moores University. Additionally, she frequently reveiws for funding bodies and journal publications.
Enterprise Interest and Activities
Caroline has worked with a range of industrial collaborators across various microbiology based projects. Examples include: identifying functional microbes within anaerobic digestion facilities; screening for efficiency of antimicrobial ability of chemicals; identifying microorganisms involved in bioplastic production; and producing valuable chemicals from waste streams. Caroline is particularly interested in working with companies looking to utilise microbial processes to gain valuable products from diverse waste streams, as well as working with agricultural industry to optimise soil health. If you are interested in any of these areas please get in touch with me to discuss.
Learning and Teaching Interests and Activities
Caroline is a Fellow of the Higher Education Academy and is currently module leader for 'Microbial Diversity and Environmental Microbiology'.
Caroline acted as programme leader for Biological Sciences before being promoted to Principal Lecturer. During this time she was involved in promoting research informed teaching. She successfully gained funds to employ several 'students as researchers' a scheme which allows students to gain research skills alongside their studies.
Alongside other Teesside colleagues Caroline recently had a publication accepted within the Student Engagement in Higher Education Journal and participated in the RAISE conference to promote student engagement.
Education/Academic qualification
PhD, Molecular Biology, Northumbria University
9 Jan 2007 → 1 Mar 2011
Award Date: 1 Mar 2011
Bachelor, BSc (Hons) Biotechnology, Northumbria University
1 Sept 2004 → 2 Jul 2007
Award Date: 2 Jul 2007
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Collaborations and top research areas from the last five years
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PhD project - using microbial communities to predict anaerobic digestion success
Orr, C. (PI)
1/03/25 → 1/03/29
Project: Research
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Mapping the Path to Pesticide-Free Agriculture: Integrating Geospatial Analysis and Farmers’ Perspectives on Adoption Readiness in Nigeria
Oludoye, O. (PI), Rashid, M. (CoI) & Orr, C. (CoI)
1/02/25 → …
Project: Research
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MSAD: Methanosarcina detection and addition for optimised anaerobic digestion
Orr, C. (PI)
1/07/23 → 30/04/24
Project: Research
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Effects of milk supplemented with fluoride and/or probiotics on controlling cariogenic biofilm growth using an in vitro experimental model
Zohoori, V. (PI), Orr, C. (CoI), Jakubovics, N. (CoI), Dean, P. (CoI), Stecksen-blicks , C. (CoI) & Twetman, S. (CoI)
1/09/22 → 31/08/24
Project: Research
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ELDER: Improving the oral health of older adults using milk supplemented with fluoride and probiotics: An interventional feasibility study and pilot RCT
Zohoori, V. (PI), Orr, C. (CoI), Twetman, S. (CoI), Stecksen-blicks , C. (CoI) & Angione, C. (CoI)
Eklund Foundation for Odontological Research & Education
1/03/22 → 31/12/24
Project: Research
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Bone Diagenesis and Extremes of Preservation in Forensic Science
Williams, R., Thompson, T., Orr, C. & Taylor, G., 24 Jan 2025, In: Human. 5, 1, 21 p., 2.Research output: Contribution to journal › Review article › peer-review
Open AccessFile29 Downloads (Pure) -
Cariogenic Biofilm Interventions Using Probiotic Lactic Acid Bacteria and Fluoride.
Milne, A., Orr, C., Jakubovics, N., Dean, P., Stecksen-blicks , C. & Zohoori, F. V., 2024, In: Journal of Dental Research. 0408.Research output: Contribution to journal › Article
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Comparative soil bacterial metabarcoding after aboveground vs. subsurface decomposition of Mus musculus
Bisker, C., Taylor, G., Carney, H., Orr, C. H., Javan, G. T. & Ralebitso-Senior, T. K., 28 Dec 2024, In: Scientific Reports. 14, 1, 15 p., 31179.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Developing a 3D strategy: Pipelines and recommendations for 3D structured light scanning of archaeological artefacts
Williams, R., Thompson, T., Orr, C. & Taylor, G., 1 Jun 2024, In: Digital Applications in Archaeology and Cultural Heritage. 33, e00338.Research output: Contribution to journal › Article › peer-review
Open Access -
Effect of Fluoride on Gut Microbiota: A Systematic Review
Yasin, M., Zohoori, F. V., Kumah, E. A., Subramanian, M., Dean, P. & Orr, C. H., 10 Mar 2024, In: Nutrition Reviews. 28 p., nuae202.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Downloads (Pure)
Press/Media
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Research to help reduce preterm births among academic's diverse projects
19/02/20
1 item of Media coverage
Press/Media: Press / Media