Research Output per year
Research Output
2019
Ceramides bind VDAC2 to trigger mitochondrial apoptosis
Dadsena, S., Bockelmann, S., Mina, J. G. M., Hassan, D. G., Korneev, S., Razzera, G., Jahn, H., Niekamp, P., Müller, D., Schneider, M., Tafesse, F. G., Marrink, S. J., Melo, M. N. & Holthuis, J. C. M., 23 Apr 2019, In : Nature Communications. 10, 1, 1832.Research output: Contribution to journal › Article
Open Access
File
The identification of small molecule inhibitors of the plant inositol phosphorylceramide synthase which demonstrate herbicidal activity
Pinneh, E. C., Mina, J. G., Stark, M. J. R., Lindell, S. D., Luemmen, P., Knight, M. R., Steel, P. G. & Denny, P. W., 1 Dec 2019, In : Scientific Reports. 9, 1, 8083.Research output: Contribution to journal › Article
Open Access
File
2018
A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7
Bockelmann, S., Mina, J. G. M., Korneev, S., Hassan, D. G., Mueller, D., Hilderink, A., Vlieg, H. C., Raijmakers, R., Heck, A. J. R., Haberkant, P. & Holthuis, J. C. M., 1 Mar 2018, In : Journal of Lipid Research. 59, 3, p. 515-530 16 p.Research output: Contribution to journal › Article
Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform
Norcliffe, J. L., Mina, J. G., Alvarez, E., Cantizani, J., de Dios-Anton, F., Colmenarejo, G., Gonzalez-Del Valle, S., Marco, M., Fiandor, J. M., Martin, J. J., Steel, P. G. & Denny, P. W., 2 Mar 2018, In : Scientific Reports. 8, 3938, 10 p.Research output: Contribution to journal › Article
Open Access
Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania
Trinconi, C. T., Miguel, D. C., Silber, A. M., Brown, C., Mina, J. G. M., Denny, P. W., Heise, N. & Uliana, S. R. B., 25 Oct 2018, In : International Journal for Parasitology: Drugs and Drug Resistance. 8, 3, p. 475-487 13 p.Research output: Contribution to journal › Article
Open Access
File
2017
ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain
Cabukusta, B., Kol, M., Kneller, L., Hilderink, A., Bickert, A., Mina, J. G. M., Korneev, S. & Holthuis, J. C. M., 25 Jan 2017, In : Scientific Reports. 7, 17 p.Research output: Contribution to journal › Article
Open Access
File
Functional and phylogenetic evidence of a bacterial origin for the first enzyme in sphingolipid biosynthesis in a phylum of eukaryotic protozoan parasites
Mina, J. G., Thye, J. K., Alqaisi, A. Q. I., Bird, L. E., Dods, R. H., Groftehauge, M. K., Mosely, J. A., Pratt, S., Shams-Eldin, H., Schwarz, R. T., Pohl, E. & Denny, P. W., 21 Jul 2017, In : Journal of Biological Chemistry. 292, 29, p. 12208-12219 12 p.Research output: Contribution to journal › Article
Open Access
File
Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site-engineering of sphingomyelin synthases
Kol, M., Panatala, R., Nordmann, M., Swart, L., van Suijlekom, L., Cabukusta, B., Hilderink, A., Grabietz, T., Mina, J. G. M., Somerharju, P., Korneev, S., Tafesse, F. G. & Holthuis, J. C. M., 23 May 2017, In : Journal of Lipid Research. 58, 5, p. 962-973 12 p.Research output: Contribution to journal › Article
Open Access
File
2013
Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii
Pratt, S., Wansadhipathi-Kannangara, N. K., Bruce, C. R., Mina, J. G., Shams-Eldin, H., Casas, J., Hanada, K., Schwarz, R. T., Sonda, S. & Denny, P. W., 1 Jan 2013, In : Molecular and Biochemical Parasitology. 187, 1, p. 43-51 9 p.Research output: Contribution to journal › Article
Open Access
2011
Exploring Leishmania major Inositol Phosphorylceramide Synthase (LmjIPCS): Insights into the ceramide binding domain
Mina, J. G., Mosely, J. A., Ali, H. Z., Denny, P. W. & Steel, P. G., 2011, In : Organic and Biomolecular Chemistry. 9, 6, p. 1823-1830 8 p.Research output: Contribution to journal › Article
2010
A plate-based assay system for analyses and screening of the Leishmania major inositol phosphorylceramide synthase
Mina, J. G., Mosely, J. A., Ali, H. Z., Shams-Eldin, H., Schwarz, R. T., Steel, P. G. & Denny, P. W., 1 Sep 2010, In : International Journal of Biochemistry and Cell Biology. 42, 9, p. 1553-1561 9 p.Research output: Contribution to journal › Article
Functional analyses of differentially expressed isoforms of the Arabidopsis inositol phosphorylceramide synthase
Mina, J. G., Okada, Y., Wansadhipathi-Kannangara, N. K., Pratt, S., Shams-Eldin, H., Schwarz, R. T., Steel, P. G., Fawcett, T. & Denny, P. W., 1 Jul 2010, In : Plant Molecular Biology. 73, 4-5, p. 399-407 9 p.Research output: Contribution to journal › Article
2009
The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target
Mina, J. G., Pan, S-Y., Wansadhipathi, N. K., Bruce, C. R., Shams-Eldin, H., Schwarz, R. T., Steel, P. G. & Denny, P. W., 1 Nov 2009, In : Molecular and Biochemical Parasitology. 168, 1, p. 16-23 8 p.Research output: Contribution to journal › Article
2005
A tandem C-H insertion-acetal cleavage sequence: stereocontrolled synthesis of substituted tetrahydrofurans
Garbi, A., Mina, JG., Steel, PG., Longstaff, T. & Vile, S., 17 Oct 2005, In : Tetrahedron Letters. 46, 42, p. 7175-7178 4 p.Research output: Contribution to journal › Article