Projects per year
Personal profile
Academic Biography
Lecturer of Bioinformatics in the School of Health and Life Sciences.
I received my undergraduate degree in Biological Sciences from Teesside University in 2019. Afterward, I undertook her PhD project ‘Integrated Microbiological and Synthetic Biology Approaches to
Increase Glycopeptide Antibiotic Production’ which was co-funded by the local SME, Hart Biologicals. I was awarded my PhD in Biochemistry and Synthetic Biology by Teesside University in 2024. Before joining as a lecturer at Teesside University I worked as a Post Doctoral Research student at the National Horizons Centre.
Learning and Teaching Interests and Activities
I am currently a lecturer for MSc Bioinformatics and I am the module leader for the courses 'R for Bioinformatics' and 'Genomic Technologies'.
Summary of Research Interests
I have a strong background in both computational and experimental biology. Current research interests focus on microbial transcriptomic data analysis, with a particular emphasis on understanding gene expression patterns and regulatory mechanisms in microbial communities. Special interests lie in investigating gene clusters and their potential activation, contributing to advancements in synthetic biology and metabolic engineering.
In addition to bioinformatics expertise, I bring significant hands-on experience in molecular biology and microbiology techniques. These include genetic engineering, where I’ve engineered microbial strains for industrial applications, nucleic acid extractions from diverse biological samples, and the heterologous expression of recombinant DNA for functional and transcriptomic studies. My work bridges the gap between in silico analysis and wet-lab experiments, ensuring a comprehensive approach to biological research. I aim to address key challenges in microbial biotechnology, from basic gene regulation studies to practical applications in industry and medicine.
I’m passionate about interdisciplinary research and advocate for collaborations between microbiology, molecular biology, and bioinformatics among students and colleagues alike.
Education/Academic qualification
PhD, Integrated Microbiological and Synthetic Biology Approaches to Increase Glycopeptide Production, Teesside University
2019 → 2024
Award Date: 16 Feb 2024
Bachelor, BSc Biological Sciences, Teesside University
2016 → 2019
Award Date: 1 Jul 2019
PGCLTHE
2024 → …
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Collaborations and top research areas from the last five years
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Investigating the Control and Molecular Architecture of Inclusion Body Formation
Butler, L. (RA), Bray, G. (RA) & Akram, S. (PI)
6/09/19 → …
Project: Research
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Integrated Microbiological and Synthetic Biology Approaches to Increase Glycopeptide Production
Butler, L. (RA) & Akram, S. (PI)
3/10/16 → 16/02/24
Project: Research
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Invasive Parasites and Global Change
Bojko, J., Roy, H. E., Burgess, A., Butler, L., Pellie, F. & Dunn, A., 31 Oct 2023, Parasites and Biological Invasions. Bojko, J., Dunn, A. M. & Blakeslee, A. M. H. (eds.). Cabi Publishing, Vol. 1. p. 115-140Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Medicines from Microbes
Butler, L., O'Hanlon, M. & Gilchrist, D., 1 Sept 2021, In: Primary Science. 169, p. 9-12Research output: Contribution to journal › Article
Open AccessFile4 Downloads (Pure) -
Tailor-made recombinant prokaryotic lectins for characterisation of glycoproteins
Fernandez-Poza, S., Padros, A., Thompson, R., Butler, L., Islam, M., Mosely, J. A., Scrivens, J. H., F Rehman, M. & Akram, M. S., 27 Feb 2021, In: Analytica Chimica Acta. 1155, 338352.Research output: Contribution to journal › Article › peer-review
Open Access -
Challenges for biosimilars: focus on rheumatoid arthritis
Akram, S., Pery, N., Butler, L., Shafiq, M. I., Batool, N., ur Rehman, M. F., Grahame-Dunn, L. G. & Yetisen, A. K., 11 Oct 2020, In: Critical Reviews in Biotechnology. 41, 1, p. 121-153 33 p.Research output: Contribution to journal › Review article › peer-review
Open Access