Research output per year
Research output per year
Personal profile
Summary of Research Interests
My research interest is genomic abnormalities and their functional roles in cancer development and progression. Currently I am studying childhood lymphoma to identify novel therapeutic targets, as well as biomarkers for stratifying high-risk patients.
The overall aim is to develop kinder and more effective therapies to improve survival and reduce treatment-related toxicity for childhood lymphoma, with a range of molecular, cellular and genomic techniques, such as gene editing with CRISPR/Cas9, multi-colour flow cytometry, microscopic fluorescence imaging, real-time quantitative PCR, Western blotting, cytogenetics and NGS sequencing.
External Roles and Professional Activities
European Hematology Association (EHA)
British Society for Haematology (BSH)
Education/Academic qualification
PhD, University of Glasgow
Oct 2007 → Nov 2011
Master, Newcastle University
Sep 2006 → Aug 2007
Bachelor, Durham University
Oct 2003 → Jun 2006
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Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma
Newman, A., Zaka, M., Zhou, P., Blain, A. E., Erhorn, A., Barnard, A., Crossland, R. E., Wilkinson, S., Enshaei, A., Zordi, J. D., Harding, F., Taj, M., Wood, K. M., Televantou6, D., Turner, S. D., Burke, G. A. A., Harrison, C. J., Bomken, S., Bacon, C. M. & Rand, V., 21 Oct 2021, In: Leukemia. e-pubResearch output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia
Ciardullo, C., Szoltysek, K., Zhou, P., Pietrowska, M., Marczak, L., Willmore, E., Enshaei, A., Walaszczyk, A., Ho, J. Y., Rand, V., Marshall, S., Hall, A., Harrison, C. J., Soundararajan, M. & Eswaran, J., 21 Dec 2021, In: Cancers. 14, 1, 23.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis
Gong, C., Krupka, J. A., Gao, J., Grigoropoulos, N. F., Giotopoulos, G., Asby, R., Screen, M., Usheva, Z., Cucco, F., Barrans, S., Painter, D., Zaini, N. B. M., Haupl, B., Bornelöv, S., Ruiz De Los Mozos, I., Meng, W., Zhou, P., Blain, A. E., Forde, S., Matthews, J. & 17 others, , 25 Aug 2021, In: Molecular Cell. 81, 19, p. 4059–4075Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Downloads (Pure) -
DAP Kinase-Related Apoptosis-Inducing Protein Kinase 2 (DRAK2) Is a Key Regulator and Molecular Marker in Chronic Lymphocytic Leukemia
Szoltysek, K., Ciardullo, C., Zhou, P., Walaszczyk, A., Willmore, E., Rand, V., Marshall, S., Hall, A., Harrison, C. J., Eswaran, J. & Soundararajan, M., 16 Oct 2020, In: International Journal of Molecular Sciences. 21, 20, 7663.Research output: Contribution to journal › Article › peer-review
Open Access -
Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif.
Zhou, P., Blain, AE., Newman, AM., Zaka, M., Chagaluka, G., Adlar, FR., Offor, UT., Broadbent, C., Chaytor, L., Whitehead, A., Hall, A., O'Connor, H., Van, N. S., Lampert, I., Bailey, S., Molyneux, E., Bacon, C. M., Bomken, S. & Rand, V., 1 Jul 2019, In: Blood advances. 3, 14, p. 2118–2127Research output: Contribution to journal › Article › peer-review
Open Access
Press / Media
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Teesside University researchers in cancer treatment breakthrough
11/09/21
1 item of Media coverage
Press/Media: Press / Media
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Pharmacists to oversee nutritional cure of diabetes?
1/10/21
1 item of Media coverage
Press/Media: Press / Media