Research output per year
Research output per year
Personal profile
Summary of Research Interests
My research interest is genomic abnormalities and their functional roles in cancer development and progression. Currently I am studying childhood lymphoma to identify novel therapeutic targets, as well as biomarkers for stratifying high-risk patients.
The overall aim is to develop kinder and more effective therapies to improve survival and reduce treatment-related toxicity for childhood lymphoma, with a range of molecular, cellular and genomic techniques, such as gene editing with CRISPR/Cas9, multi-colour flow cytometry, microscopic fluorescence imaging, real-time quantitative PCR, Western blotting, cytogenetics and NGS sequencing.
External Roles and Professional Activities
European Hematology Association (EHA)
British Society for Haematology (BSH)
Education/Academic qualification
Bachelor, BSc (Hons) in Cell Biology , Durham University
Master, MRes in Medical and Molecular Biosciences (Cancer Research) , Newcastle University
PhD, PhD in Haematology, University of Glasgow
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Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development
Danilenko, M., Zaka, M., Keeling, C., Crosier, S., Lyman, S., Finetti, M., Williamson, D., Hussain, R., Coxhead, J., Zhou, P., Hill, R. M., Hicks, D., Rand, V., Joshi, A., Schwalbe, E. C., Bailey, S. & Clifford, S. C., 1 Sept 2022, In: Acta Neuropathologica. 144, 3, p. 565-578 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Downloads (Pure) -
Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma
Newman, A., Zaka, M., Zhou, P., Blain, A. E., Erhorn, A., Barnard, A., Crossland, R. E., Wilkinson, S., Enshaei, A., Zordi, J. D., Harding, F., Taj, M., Wood, K. M., Televantou6, D., Turner, S. D., Burke, G. A. A., Harrison, C. J., Bomken, S., Bacon, C. M. & Rand, V., 21 Oct 2021, In: Leukemia. e-pubResearch output: Contribution to journal › Article › peer-review
Open AccessFile89 Downloads (Pure) -
Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia
Ciardullo, C., Szoltysek, K., Zhou, P., Pietrowska, M., Marczak, L., Willmore, E., Enshaei, A., Walaszczyk, A., Ho, J. Y., Rand, V., Marshall, S., Hall, A., Harrison, C. J., Soundararajan, M. & Eswaran, J., 21 Dec 2021, In: Cancers. 14, 1, 23.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Downloads (Pure) -
Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis
Gong, C., Krupka, J. A., Gao, J., Grigoropoulos, N. F., Giotopoulos, G., Asby, R., Screen, M., Usheva, Z., Cucco, F., Barrans, S., Painter, D., Zaini, N. B. M., Haupl, B., Bornelöv, S., Ruiz De Los Mozos, I., Meng, W., Zhou, P., Blain, A. E., Forde, S., Matthews, J., & 17 others, 25 Aug 2021, In: Molecular Cell. 81, 19, p. 4059–4075Research output: Contribution to journal › Article › peer-review
Open AccessFile81 Downloads (Pure) -
DAP Kinase-Related Apoptosis-Inducing Protein Kinase 2 (DRAK2) Is a Key Regulator and Molecular Marker in Chronic Lymphocytic Leukemia
Szoltysek, K., Ciardullo, C., Zhou, P., Walaszczyk, A., Willmore, E., Rand, V., Marshall, S., Hall, A., Harrison, C. J., Eswaran, J. & Soundararajan, M., 16 Oct 2020, In: International Journal of Molecular Sciences. 21, 20, 7663.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Pharmacists to oversee nutritional cure of diabetes?
1/10/21
1 item of Media coverage
Press/Media: Press / Media
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Teesside University researchers in cancer treatment breakthrough
11/09/21
1 item of Media coverage
Press/Media: Press / Media
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