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Personal profile

Academic Biography

Muhammad Safwan Akram is working at School of Science & Engineering as a Senior Lecturer in Biological & Process Engineering. He has previously worked as an Assistant Professor at University of the Punjab, Lahore, Pakistan. Safwan obtained his PhD in Analytical
Biotechnology from the Department of Chemical Engineering and Biotechnology, University of Cambridge where he also did his post-doc developing low cost diagnostics. Prior to that he completed his M.Phil
in Bioscience Enterprise under the auspices of Cambridge/MIT Partnership. His work has been published in reputed journals like Nature Biotechnology, Lab on a Chip & Annual Reviews of Analytical Chemistry. He has been awarded Medimmune Award and CambridgeSens Innovative Idea award for research excellence. He provides consultancy to venture capital funds, biotech and pharma companies. During his academic career, he has taught courses on Protein design and engineering, Recombinant DNA Technology and Stem Cells, Biosensors, Technology Enterprise and Pharmaceutical Biotechnology.

Safwan was voted by the students to win university wide Star award for most outstanding teaching . Safwan is also serving as the Enterprise champion for School of Science, Engineering & Design.

Summary of Research Interests

  • Low cost diagnostics for various biotechnology applications
  • Biomimetics for sensors and fermentation applications
  • Bioactive scaffolds for Tissue Engineering
  • Exploring relationship between Inclusion Bodies (IBs) and cell viability through genomic and proteomic tools
  • Paper based diagnostics to determine drug quality
  • Polymorphism in amyloid proteins
  • Start up valuations of Biotech businesses 

Safwan’s lab is looking for PhD students for the above-mentioned projects. If interested e-mail him directly.

Safwan’s laboratory has won £140’000 funding from Innovate UK to develop protein purification strategies based on glycosylation patterns. The laboratory is working in close collaboration with Glycoselect Ltd. The laboratory has won further funding to the tune of £117’000 from ERDF to work on the development of cost effective production of biochemicals used in Haemostatis testing in collaboration with Hart Innovations Ltd. 

Enterprise Interest and Activities

Dr. M. Safwan Akram has been involved with a start-up “YourBug” and a pharma company named “Renacon Pharma”. He is always on a look out for projects worth commercialising and making a difference to society.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Thiophenes Chemical Compounds
Cholinesterase Inhibitors Chemical Compounds
Ligands Chemical Compounds
Screening Chemical Compounds
Crystal structure Chemical Compounds
Metals Chemical Compounds
Point-of-Care Systems Medicine & Life Sciences
Quinazolines Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2009 2017

30 Downloads (Pure)

Synthesis, biological evaluation and docking studies of 2,3-dihydroquinazolin-4(1H)-one derivatives as inhibitors of cholinesterases

Sarfraz, M., Sultana, N., Rashid, U., Akram, M. S., Sadiq, A. & Tariq, M. I. M. I., 17 Jan 2017, In : Bioorganic Chemistry. p. -

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Cholinesterase Inhibitors
Derivatives
Enzymes
Lead compounds
Inhibitory Concentration 50
14 Downloads (Pure)

Synthesis, crystal structure determination, biological screening and docking studies of N 1 -substituted derivatives of 2,3-dihydroquinazolin-4(1 H )-one as inhibitors of cholinesterases

Sultana, N., Sarfraz, M., Tanoli, S. T., Akram, M. S., Sadiq, A., Rashid, U. & Tariq, M. I. M. I., 17 Apr 2017, In : Bioorganic Chemistry. 72, p. 256-267

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Quinazolines
Cholinesterase Inhibitors
Cholinesterases
Alkylation
Structure-Activity Relationship
9 Downloads (Pure)

Antimicrobial metal-based thiophene derived compounds

Yasmeen, S., Sumrra, S. H. S., Akram, M. S. & Chohan, Z. H., 21 Oct 2016, In : Journal of Enzyme Inhibition and Medicinal Chemistry. p. -

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Thiophenes
Schiff Bases
Candida
Metals
Pathogens
16 Downloads (Pure)

Metal-based ethanolamine-derived compounds: a note on their synthesis, characterization and bioactivity

Amjad, M., Sumrra, S. H. S., Akram, M. S. & Chohan, Z. H., 24 Aug 2016, In : Journal of Enzyme Inhibition and Medicinal Chemistry. p. -

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Ethanolamine
Metals
Ligands
Ethanolamines
Microsporum

Applications of Paper-Based Diagnostics

Akram, M. S., Daly, R., da Cruz Vasconcellos, F., Yetisen, A. K., Hutchings, I. & Hall, E. A., 2015, Lab-on-a-Chip Devices and Micro-Total Analysis Systems. p. -

Research output: Chapter in Book/Report/Conference proceedingChapterResearch