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Accepting PhD Students

20022019

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Personal profile

Academic Biography

Current Position

Professor of Biosciences and Head of Biosciences Research

National Horizons Centre, Darlington, UK (https://www.tees.ac.uk/nhc/)

School of Health and Life Sciences, Teesside University, Middlesbrough, UK (https://www.tees.ac.uk/schools/shls/)

 

I lead the multi-disciplinary Biosciences research at the new National Horizons Centre and the School of Health and Life Sciences. The NHC brings industry, education, healthcare and academia together, to provide the Biosciences and Health sector with knowledge, skills, talent and facilities to support its development and growth. This provides access to expertise and state-of-the-art equipment for students and researchers. Please contact me if you would like further information or to discuss potential collaborations and opportunities.

 

Rand Lab - Cancer Genomics and Global Health

The overall aims of my research is to understand the biology of lymphoma and other cancers in order to identify biomarkers and develop new treatment strategies to reduce treatment-related toxicity in order to improve outcome of relapsed/refractory disease. Using a combination of cutting-edge techniques we are determining the presence, frequency and structure of genetic abnormalities in childhood and adult cancers in the UK, Africa and beyond. We are investigating the clinical importance of these genetic abnormalities by correlating the genetic data with clinical information and investigating the role of these abnormalities in the cancer cell.

Qualifications

2004 PhD Genomics and Bioinformatics, University of Cambridge/Wellcome Trust Sanger Institute

1999 First Class BSc(Hons) Biomedical Sciences, University of Bradford

 

Previous Positions

Sept 2012-Sept 2019 Bloodwise (formerly Leukaemia and Lymphoma Research) Senior Bennett Fellow and Lymphoma Genomics Group Leader, Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, UK

Sept 2010-August 2012 Lecturer in Cancer Genetics, Northern Institute for Cancer Research, Newcastle University

Sept 2008-August 2010 Lecturer Cancer Genetics in Leukaemia Research Cytogenetics Group (LRCG), Northern Institute for Cancer Research, Newcastle University

Jan 2006-Aug 2008 Postdoctoral Research Fellow, Children's Brain Tumour Research Centre, University of Nottingham

Jan 2004-Dec 2005 Postdoctoral Research Fellow, Department of Neurosurgery, Johns Hopkins University, US

 

Membership and external positions

British Society of Haematology (BSH)

Children's Cancer & Leukaemia Group (CCLG)

Cambridge Philosophical Society

External Examiner Cancer Biology Specialist Royal College of Radiologists, Lincoln’s Inn Field, London

Children’s Cancer and Leukaemia Group Biological Studies Committee Member

Deputy Director for the UniAlliance Doctoral Training Alliance (DTA) in Applied Biosciences for Health

 

Follow @vikkirand, @RandLabUK, @TU_NHC, @TeessideUni

External positions

Associate , Newcastle University

31 Oct 2019 → …

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Research Output

Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif.

Zhou, P., Blain, AE., Newman, AM., Zaka, M., Chagaluka, G., Adlar, FR., Offor, UT., Broadbent, C., Chaytor, L., Whitehead, A., Hall, A., O'Connor, H., Van, N. S., Lampert, I., Bailey, S., Molyneux, E., Bacon, C. M., Bomken, S. & Rand, V., 1 Jul 2019, In : Blood advances. 3, 14, p. 2118–2127

Research output: Contribution to journalArticle

Open Access
  • Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma.

    Noble, R. A., Bell, N., Blair, H., Sikka, A., Thomas, H., Phillips, N., Nakjang, S., Miwa, S., Crossland, R., Rand, V., Televantou, D., Long, A., Keun, H. C., Bacon, C. M., Bomken, S., Critchlow, S. E. & Wedge, S. R., 31 Jul 2017, In : Haematologica. 102, p. 1247-1257 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia.

    Gabriel, A. S., Lafta, F. M., Schwalbe, E. C., Nakjang, S., Cockell, S. J., Iliasova, A., Enshaei, A., Schwab, C., Rand, V., Clifford, S. C., Kinsey, S. E., Mitchell, C. D., Vora, A., Harris, C. J., Moorman, A. V. & Strathdee, G., 3 Aug 2015, In : Epigenetics. 10, 8, p. 717-726 10 p.

    Research output: Contribution to journalArticle

    Open Access
  • c-MYC is a radiosensitive locus in human breast cells.

    Wade, MA., Sunter, NJ., Fordham, SE., Long, A., Masic, D., Russell, LJ., Harrison, CJ., Rand, V., Elstob, C., Bown, N., Rowe, D., Lowe, C., Cuthbert, G., Bennett, S., Crosier, S., Bacon, CM., Onel, K., Scott, K., Scott, D., Travis, LB. & 2 others, May, FEB. & Allan, JM., 22 Dec 2014, In : Oncogene. 34, p. 4985–4994 10 p.

    Research output: Contribution to journalArticle

    Open Access
  • Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia.

    Li, Y., Schwab, C., Ryan, S., Papaemmanuil, E., Robinson, H. M., Jacobs, P., Moorman, A. V., Dyer, S., Borrow, J., Griffiths, M., Heerema, N. A., Carroll, A. J., Talley, P., Bown, N., Telford, N., Ross, F., Gaunt, L., McNally, R., Young, B., Sinclair, P. & 14 others, Rand, V., Teixeira, M., Joseph, O., Robinson, B., Maddison, M., Dastugue, N., Vandenberghe, P., Haferlach, C., Stephens, P., Cheng, J., Van Loo, P., Stratton, M., Campbell, P. & Harrison, CJ., Mar 2014, In : Nature. 508, p. 98-102 5 p.

    Research output: Contribution to journalArticle

    Open Access