Exploring Robotic Assisted Thoracic Surgery (RATS) for lung cancer: Does RATS result in improved functional outcomes compared to thoracotomy and how do patients appraise the experience of undergoing RATS?

Project: Research

Description

Background
Surgery for lung cancer can be performed using open (thoracotomy) or minimally invasive techniques (Video Assisted Thoracic Surgery (VATS)). Despite being associated with fewer postoperative complications (PPCs) VATS is difficult to perform and is only used by 20-44% of thoracic surgeons in the UK. Robotic-Assisted Thoracic Surgery (RATS) maybe a more attractive minimally invasive approach. To date, no studies have explored the impact of RATS on exercise capacity or physical activity and although 1 study has looked at Heath Related Quality of Life (HRQOL) post-RATS compared to an open technique indicators of surgical technique were not controlled for. Furthermore, we have little understanding of patients’ experience of RATS.
Aims
1. To examine the variability of change in exercise capacity and health-related quality of life (HRQOL) between those
who receive thoracotomy V RATS.
2. To compare the difference in post-operative physical activity (step and activity count), across 7 days, in those who
receive thoracotomy V RATS.
3. To explore the manner in which patients appraise their experience of undergoing RATS.

Methods:
A mixed-method, multi-center study will be undertaken, utilizing a prospective quasi-experimental study design and an interpretive phenomenological approach. 80 individuals, referred for a lung lobectomy with a primary or secondary diagnosis of lung cancer, will complete outcomes assessed at 4 time-points. The Incremental Shuttle Walk Test (ISWT) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ C30) and the EORTC Lung Cancer module (EORTC QLQ LC13) will be completed at: baseline, 3-6 days postsurgery,
6-weeks post-surgery and at 3-month follow up. Patients will wear an activity monitor immediately post surgery until 1-week post-discharge. Step and activity counts will be recorded. In-depth interviews will be conducted with up to 15 patients who underwent RATS to explore the manner in which patients appraise their experience of RATS.
AcronymROSE
StatusActive
Effective start/end date1/07/17 → 31/12/19