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2019
80 Downloads (Pure)

Ancient role of vasopressin/oxytocin-type neuropeptides as regulators of feeding revealed in an echinoderm

Odekunle, E. A., Semmens, D. C., Martynyuk, N., Tinoco, A. B., Garewal, A. K., Patel, R. R., Blowes, L. M., Zandawala, M., Delroisse, J., Slade, S. E., Scrivens, J. H., Egertová, M. & Elphick, M. R., 31 Jul 2019, In : BMC Biology. 17, 1, p. 60 60.

Research output: Contribution to journalArticle

Open Access
File
Starfish
vasopressin
oxytocin
echinoderm
neuropeptides

Characterisation of intact hemoglobin variants utilising a cyclic ion mobility-enabled quadrupole time-of-flight (Q-cIM-oaToF) mass spectrometer

Alkawi, AHMAD., Scrivens, J., Taylor, G., Akram, S., Palmer, M., Ujma, J., Giles, K., Williams, J. & Edgeworth, M., 2019, p. WP483.

Research output: Contribution to conferencePoster

Utilisation of enhanced shape selective information obtained from a cyclic ion mobility-enabled-mass spectrometer for the characterisation of complex mixtures

Mehboob, J., Scrivens, J., Taylor, G., Akram, S., Ujma, J., Giles, K., Portwood, D., Navarro, P. & Williams, J. P., 5 Sep 2019.

Research output: Contribution to conferencePoster

Utilisation of enhanced shape selective information obtained from a cyclic ion mobility-enabled-mass spectrometer for the characterisation of complex mixtures

Mehboob, J., Scrivens, J., Taylor, G., Akram, S., Palmer, M., Ujma, J., Giles, K., Williams, J., Portwood, D. & Navarro, P., 2019, p. TP502.

Research output: Contribution to conferencePoster

2018
2 Citations (Scopus)
98 Downloads (Pure)

Discovery and functional characterisation of a luqin-type neuropeptide signalling system in a deuterostome

Yañez-Guerra, L. A., Delroisse, J., Barreiro-Iglesias, A., Slade, S. E., Scrivens, J. H. & Elphick, M. R., 8 May 2018, In : Scientific Reports. 8, 1, 14 p., 7220.

Research output: Contribution to journalArticle

Open Access
File
neuropeptides
Asterias rubens
receptors
Chordata
Asteroidea
1 Citation (Scopus)
86 Downloads (Pure)

Native electrospray mass spectrometry approaches to probe the interaction between zinc and an anti-angiogenic peptide from histidine-rich glycoprotein

Martin, E. M., Kondrat, F. D. L., Stewart, A. J., Scrivens, J. H., Sadler, P. J. & Blindauer, C. A., 5 Jun 2018, In : Scientific Reports. 8, 1, 8646.

Research output: Contribution to journalArticle

Open Access
File
Angiogenic Proteins
Mass spectrometry
Zinc
Ions
Peptides
2016
3 Citations (Scopus)

Applications of traveling wave ion mobility-mass spectrometry

Thalassinos, K. & Scrivens, J., 19 Apr 2016, Applications of Ion Trapping Devices. CRC Press, Vol. 5. p. 205-236 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Travelling-wave ion mobility and negative ion fragmentation of high-mannose N-glycans

Harvey, D. J., Scarff, C. A., Edgeworth, M., Struwe, W. B., Pagel, K., Thalassinos, K., Crispin, M. & Scrivens, J., 4 Mar 2016, In : Journal of Mass Spectrometry. 51, 3, p. 219-235

Research output: Contribution to journalArticle

Open Access
Mannose
Isomers
Polysaccharides
Negative ions
Ions

Travelling-wave ion mobility mass spectrometry and negative ion fragmentation of hybrid and complex N-glycans

Harvey, D. J., Scarff, C. A., Edgeworth, M., Pagel, K., Thalassinos, K., Struwe, W. B., Crispin, M. & Scrivens, J., 31 Jul 2016, In : Journal of Mass Spectrometry. 51, 11, p. 1064-1079

Research output: Contribution to journalArticle

Mass spectrometry
Polysaccharides
Negative ions
Ions
Isomers
87 Downloads (Pure)

Urbilaterian origin of paralogous GnRH and corazonin neuropeptide signalling pathways

Tian, S., Zandawala, M., Beets, I., Baytemur, E., Slade, S. E., Scrivens, J. & Elphick, M. R., 28 Jun 2016, In : Scientific Reports. p. - 28788 (2016).

Research output: Contribution to journalArticle

Open Access
File
Neuropeptides
Gonadotropin-Releasing Hormone
Vertebrates
Asterias
Starfish
2015

Global and Local Conformation of Human IgG Antibody Variants Rationalizes Loss of Thermodynamic Stability

Edgeworth, M., Phillips, J. J., Lowe, D. C., Kippen, A. D., Higazi, D. R. & Scrivens, J., 7 Dec 2015, In : Angewandte Chemie International Edition. p. -

Research output: Contribution to journalArticle

Open Access
Antibodies
Conformations
Thermodynamic stability
Mass spectrometry
Proteins
Open Access
Mass spectrometry
Mass Spectrometry
Ions
Recovery
Polysaccharides
88 Downloads (Pure)

Protomers of Benzocaine: Solvent and Permittivity Dependence

Warnke, S., Seo, J., Boschmans, J., Sobott, F., Scrivens, J., Bleiholder, C., Bowers, M. T., Gewinner, S., Schöllkopf, W., Pagel, K. & von Helden, G., 11 Mar 2015, In : Journal of the American Chemical Society. p. -

Research output: Contribution to journalArticle

Open Access
File
Benzocaine
Protein Subunits
Permittivity
Gases
Protonation
2014

5.4 First trimester Angiotensinogen: Kallikrein ratio is raised in women who develop severe early-onset pre-eclampsia

Breslin, E., Slade, S. E., Akolekar, R., Nicolaides, K., Scrivens, J. & Quenby, S., 9 Jun 2014, In : Archives of Disease in Childhood - Fetal and Neonatal Edition. p. -

Research output: Contribution to journalArticle

Open Access
Angiotensinogen
Kallikreins
Pre-Eclampsia
First Pregnancy Trimester
Uterine Artery

Estimating Collision Cross Sections of Negatively Charged N-Glycans using Traveling Wave Ion Mobility-Mass Spectrometry

Hofmann, J., Struwe, W. B., Scarff, C. A., Scrivens, J., Harvey, D. J. & Pagel, K., 30 Sep 2014, In : Analytical Chemistry. p. -

Research output: Contribution to journalArticle

Open Access
Mass spectrometry
Polysaccharides
Ions
Calibration
Carbohydrates

Fragmentation of negative ions from N-linked carbohydrates: Part 6. Glycans containing one N-acetylglucosamine in the core

Harvey, D. J., Edgeworth, M., Krishna, B. A., Bonomelli, C., Allman, S. A., Crispin, M. & Scrivens, J., 30 Sep 2014, In : Rapid Communications in Mass Spectrometry. p. -

Research output: Contribution to journalArticle

Open Access
Acetylglucosamine
Polysaccharides
Negative ions
Carbohydrates
Ions

Mass Spectrometric Strategies to Improve the Identification of Pt(II)-Modification Sites on Peptides and Proteins

Li, H., Snelling, J. R., Barrow, M. P., Scrivens, J., Sadler, P. J. & O’Connor, P. B., 21 May 2014, In : Journal of the American Society for Mass Spectrometry. p. -

Research output: Contribution to journalArticle

Open Access
Platinum
Cisplatin
Amines
Peptides
Binding Sites
83 Downloads (Pure)

Structural Plasticity of the Semliki Forest Virus Glycome upon Interspecies Transmission

Crispin, M., Harvey, D. J., Bitto, D., Bonomelli, C., Edgeworth, M., Scrivens, J., Huiskonen, J. T. & Bowden, T. A., 28 Jan 2014, In : Journal of Proteome Research. 13, 3, p. 1702-1712

Research output: Contribution to journalArticle

Open Access
File
Semliki forest virus
Viruses
Polysaccharides
Plasticity
Glycoproteins
97 Downloads (Pure)

Uukuniemi Phlebovirus Assembly and Secretion Leave a Functional Imprint on the Virion Glycome

Crispin, M., Harvey, D. J., Bitto, D., Halldorsson, S., Bonomelli, C., Edgeworth, M., Scrivens, J., Huiskonen, J. T. & Bowden, T. A., 18 Jun 2014, In : Journal of Virology. 88, 17, p. 10244-10251

Research output: Contribution to journalArticle

Open Access
File
Phlebovirus
Uukuniemi virus
virion
Virion
secretion
2013
20 Citations (Scopus)

Discovery of a novel neurophysin-associated neuropeptide that triggers cardiac stomach contraction and retraction in starfish

Semmens, D. C., Dane, R. E., Pancholi, M. R., Slade, S. E., Scrivens, J. & Elphick, M. R., 1 Nov 2013, In : Journal of Experimental Biology. 216, 21, p. 4047-4053 7 p.

Research output: Contribution to journalArticle

Neurophysins
Starfish
Asteroidea
neuropeptides
Neuropeptides
1 Citation (Scopus)

Is the higher risk of cardiovascular disease amongst South Asian populations linked to abnormalities of haemoglobin? A preliminary case control study

Patel, J. V., Chackathayil, J., Gammon, B., Tracey, I., Lovick, A., Gill, P. S., Banerjee, A., Scarff, C. A., Scrivens, J., Lip, G. Y. H. & Hughes, E. A., 1 Jan 2013, In : Atherosclerosis. 226, 1, p. 198-200 3 p.

Research output: Contribution to journalArticle

Case-Control Studies
Hemoglobins
Cardiovascular Diseases
Carotid Intima-Media Thickness
Population
13 Citations (Scopus)

Localisation of adenine nucleotides in heat-stabilised mouse brains using ion mobility enabled MALDI imaging

Blatherwick, E. Q., Svensson, C. I., Frenguelli, B. G. & Scrivens, J., 1 Jul 2013, In : International Journal of Mass Spectrometry. 345-347, p. 19-27 9 p.

Research output: Contribution to journalArticle

Adenine Nucleotides
adenines
nucleotides
Nucleotides
brain
5 Citations (Scopus)

Resolution of a paradox by native mass spectrometry: Facile occupation of all four metal binding sites in the dimeric zinc sensor SmtB

Kondrat, F. D. L., Kowald, G. R., Scarff, C. A., Scrivens, J. & Blindauer, C. A., 28 Jan 2013, In : Chemical Communications. 49, 8, p. 813-815 3 p.

Research output: Contribution to journalArticle

Binding sites
Dimers
Mass spectrometry
Zinc
Metals
39 Citations (Scopus)

Travelling wave ion mobility and negative ion fragmentation for the structural determination of N-linked glycans

Harvey, D. J., Scarff, C. A., Edgeworth, M., Crispin, M., Scanlan, C. N., Sobott, F., Allman, S., Baruah, K., Pritchard, L. & Scrivens, J., 1 Aug 2013, In : Electrophoresis. 34, 16, p. 2368-2378 11 p.

Research output: Contribution to journalArticle

Polysaccharides
Negative ions
Ions
Isomers
Fetuins
2012
14 Citations (Scopus)

A role for sigma factor σE in Corynebacterium pseudotuberculosis resistance to nitric oxide/peroxide stress

Pacheco, L. G. C., Castro, T. L. P., Carvalho, R. D., Moraes, P. M., Dorella, F. A., Carvalho, N. B., Slade, S. E., Scrivens, J., Feelisch, M., Meyer, R., Miyoshi, A., Oliveira, S. C., Dowson, C. G. & Azevedo, V., 1 Jan 2012, In : Frontiers in Microbiology. 3, APR

Research output: Contribution to journalArticle

Corynebacterium pseudotuberculosis
Peroxides
Nitric Oxide
Bacteria
Sigma Factor
8 Citations (Scopus)

Characterization of complex polysorbate formulations by means of shape-selective mass spectrometry

Snelling, J. R., Scarff, C. A. & Scrivens, J., 7 Aug 2012, In : Analytical Chemistry. 84, 15, p. 6521-6529 9 p.

Research output: Contribution to journalArticle

Polysorbates
Mass spectrometry
Ethylene Oxide
Molecular mass
Atmospheric pressure
6 Citations (Scopus)

Comparison of one- and two-dimensional liquid chromatography approaches in the label-free quantitative analysis of Methylocella silvestris

Patel, N. A., Crombie, A., Slade, S. E., Thalassinos, K., Hughes, C., Connolly, J. B., Langridge, J., Murrell, J. C. & Scrivens, J., 7 Sep 2012, In : Journal of Proteome Research. 11, 9, p. 4755-4763 9 p.

Research output: Contribution to journalArticle

Liquid chromatography
Liquid Chromatography
Labels
High pressure liquid chromatography
Chemical analysis
9 Citations (Scopus)

Design and application of a data-independent precursor and product ion repository

Thalassinos, K., Vissers, J. P. C., Tenzer, S., Levin, Y., Thompson, J. W., Daniel, D., Mann, D., DeLong, M. R., Moseley, M. A., America, A. H., Ottens, A. K., Cavey, G. S., Efstathiou, G., Scrivens, J., Langridge, J. I. & Geromanos, S. J., 1 Oct 2012, In : Journal of the American Society for Mass Spectrometry. 23, 10, p. 1808-1820 13 p.

Research output: Contribution to journalArticle

Ions
Peptides
Ionization
Complement System Proteins
Proteins
5 Citations (Scopus)

Fibrillation of transferrin

Booyjz̈sen, C., Scarff, C. A., Moreton, B., Portman, I., Scrivens, J., Costantini, G. & Sadler, P. J., 1 Mar 2012, In : Biochimica et Biophysica Acta - General Subjects. 1820, 3, p. 427-436 10 p.

Research output: Contribution to journalReview article

Transferrin
Transferrins
Agglomeration
Mass spectrometry
Mass Spectrometry
37 Citations (Scopus)

MALDI-MS/MS with traveling wave ion mobility for the structural analysis of N-Linked Glycans

Harvey, D. J., Scarff, C. A., Crispin, M., Scanlan, C. N., Bonomelli, C. & Scrivens, J., 1 Nov 2012, In : Journal of the American Society for Mass Spectrometry. 23, 11, p. 1955-1966 12 p.

Research output: Contribution to journalArticle

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Structural analysis
Polysaccharides
Ions
Negative ions
34 Citations (Scopus)

New structural insights into mechanically interlocked polymers revealed by ion mobility mass spectrometry

Scarff, C. A., Snelling, J. R., Knust, M. M., Wilkins, C. L. & Scrivens, J., 6 Jun 2012, In : Journal of the American Chemical Society. 134, 22, p. 9193-9198 6 p.

Research output: Contribution to journalArticle

Mass spectrometry
Mass Spectrometry
Polymers
Ions
Topology
2011
35 Citations (Scopus)

A combined approach for comparative exoproteome analysis of Corynebacterium pseudotuberculosis

Pacheco, L. G., Slade, S. E., Seyffert, N., Santos, A. R., Castro, T. L., Silva, W. M., Santos, A. V., Santos, S. G., Farias, L. M., Carvalho, M. A., Pimenta, A. M., Meyer, R., Silva, A., Scrivens, J., Oliveira, S. C., Miyoshi, A., Dowson, C. G. & Azevedo, V., 19 Jan 2011, In : BMC Microbiology. 11, 12.

Research output: Contribution to journalArticle

Corynebacterium pseudotuberculosis
Proteins
Bacteria
Lymphadenitis
Bacterial Proteins
54 Citations (Scopus)

Bacterial flavin-containing monooxygenase is trimethylamine monooxygenase

Chen, Y., Patel, N. A., Crombie, A., Scrivens, J. & Murrell, J. C., 25 Oct 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 43, p. 17791-17796 6 p.

Research output: Contribution to journalArticle

dimethylaniline monooxygenase (N-oxide forming)
Roseobacter
Oceans and Seas
Rhodobacteraceae
Carbon
47 Citations (Scopus)

Ion mobility mass spectrometry for extracting spectra of n-glycans directly from incubation mixtures following glycan release: Application to glycans from engineered glycoforms of intact, folded HIV gp120

Harvey, D. J., Sobott, F., Crispin, M., Wrobel, A., Bonomelli, C., Vasiljevic, S., Scanlan, C. N., Scarff, C. A., Thalassinos, K. & Scrivens, J., 1 Mar 2011, In : Journal of the American Society for Mass Spectrometry. 22, 3, p. 568-581 14 p.

Research output: Contribution to journalArticle

Viruses
Mass spectrometry
Polysaccharides
Mass Spectrometry
HIV
32 Citations (Scopus)

Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism

Blatherwick, E. Q., Van Berkel, G. J., Pickup, K., Johansson, M. K., Beaudoin, M. E., Cole, R. O., Day, J. M., Iverson, S., Wilson, I. D., Scrivens, J. & Weston, D. J., 1 Jan 2011, In : Xenobiotica. 41, 8, p. 720-734 15 p.

Research output: Contribution to journalReview article

Atmospheric Pressure
Metabolism
Atmospheric pressure
Ionization
Sampling