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2019
111 Downloads (Pure)

A new family of cell surface located purine transporters in Microsporidia and related fungal endoparasites

Major, P., Sendra, K. M., Dean, P., Williams, T. A., Watson, A. K., Thwaites, D. T., Embley, T. M. & Hirt, R. P., 29 Jul 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
File
Microsporidia
Parasites
Genes
Genome
Membrane Transport Proteins

Regulation of phagosome functions by post-translational modifications: a new paradigm

Dean, P., Heunis, T., Härtlova, A. & Trost, M., 1 Feb 2019, In : Current Opinion in Chemical Biology. 48, p. 73-80 8 p.

Research output: Contribution to journalArticle

Open Access
phagosomes
post-translational modification
organelles
antigen presentation
latex

Stealing is the Deal: Parasites that grow within animal cells use a family of transport proteins to take nucleotides, the building blocks of DNA, from their hosts.

Major, P., Sendra, K., Dean, P., Williams, T. A., Watson, A. K., Thwaites, D. T., Embley, T. M. & Hirt, R. P., 19 Aug 2019, In : eLife.

Research output: Contribution to journalComment/debate

Open Access
Theft
Carrier Proteins
Parasites
Animals
Nucleotides
2018
84 Downloads (Pure)

Transporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites

Dean, P., Sendra, K. M., Williams, T. A., Watson, A. K., Major, P., Nakjang, S., Kozhevnikova, E., Goldberg, A. V., Kunji, E. R. S., Hirt, R. P. & Embley, T. M., 27 Apr 2018, In : Nature Communications. 9, 1

Research output: Contribution to journalArticle

Open Access
File
Microsporidia
parasites
transporter
nucleotides
genes
2017
94 Downloads (Pure)

Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis

Freibert, S., Goldberg, A. V., Hacker, C., Molik, S., Dean, P., Williams, T. A., Nakjang, S., Long, S., Sendra, K., Bill, E., Heinz, E., Hirt, R. P., Lucocq, J. M., Embley, T. M. & Lill, R., 4 Jan 2017, In : Nature Communications. 8, p. 13932

Research output: Contribution to journalArticle

Open Access
File
biosynthesis
Biosynthesis
conservation
Conservation
Protein S
2016
81 Downloads (Pure)

Microsporidia: Why Make Nucleotides if You Can Steal Them?

Dean, P., Hirt, R. P. & Embley, T. M., 17 Nov 2016, In : PLoS Pathogens. 12, 11, 13 p., e1005870.

Research output: Contribution to journalArticle

Open Access
File
Microsporidia
Nucleotides
Adenosine Triphosphate
Genome
Nucleotide Transport Proteins

Visualizing the Translocation and Localization of Bacterial Type III Effector Proteins by Using a Genetically Encoded Reporter System

Gawthorne, J. A., Audry, L., Mcquitty, C., Dean, P., Christie, J. M., Enninga, J. & Roe, A. J., 1 May 2016, In : Applied and Environmental Microbiology. 82, 9, p. 2700-2708

Research output: Contribution to journalArticle

Open Access
Bacterial Translocation
translocation
type III secretion system
Oxygen
oxygen