Antibiotic Resistance in Gram-Negative Bacteria: The Threat from the Pink Corner

Antibiotic resistance in Gram-negative bacteria is a formidable challenge in modern medicine [1], often referred to as the threat from the “pink corner” due to the pink staining of these bacteria during Gram staining. This Special Issue, “Antibiotic Resistance in Gram-Negative Bacteria: The Threat from the Pink Corner,” delves into this pressing issue through a compilation of eight research articles and two review papers. The collected works provide a multi-faceted exploration of the mechanisms driving resistance and innovative approaches to the treatment of infectious diseases. By shedding light on the resilience of Gram-negative pathogens, this Special Issue aims to advance our understanding and inform strategies to combat the growing threat of antibiotic resistance, ultimately contributing to global public health efforts. In this Special Issue, multiple aspects of the topic are comprehensively addressed, with particular emphasis on the genomic characterization of multidrug resistance in Klebsiella pneumoniae, Acinetobacter baumannii, and Escherichia coli. Additionally, the antibacterial activity of novel compounds and the mechanisms underlying the development of resistance are thoroughly explored.