Abstract
Mutant libraries of avermectin-producing Streptomyces avermitilis strains were constructed by different mutagenesis strategies. A metric was applied to assess the mutation spectrum by calculating the distribution of average phenotypic distance of each population. The results showed for the first time that a microgravity environment could introduce larger phenotype distribution and diversity than UV and N-methyl-N-nitro-N-nitrosoguanidine (NTG) could.
Original language | English |
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Pages (from-to) | 4583-6 |
Number of pages | 4 |
Journal | Applied and Environmental Microbiology |
Volume | 76 |
Issue number | 13 |
DOIs | |
Publication status | Published - Jul 2010 |