Association Between Weight Status and Executive Function in Young Adults

Mohammad Narimani, Samad Esmaeilzadeh, Liane Azevedo, Akbar Moradi, Behrouz Heidari, Malahat Kashfi Moghadam

Research output: Contribution to journalArticleResearchpeer-review

16 Downloads (Pure)

Abstract

Background and objectives: To explore the association between weight status and executive function in young adults. Materials and Methods: Ninety-seven young males (age 17–26 years) underwent adiposity and body composition measurements using body composition analyzer. Inhibitory control and working memory were measured using the Cambridge Neuropsychological Test Battery (CANTAB). Results: Multiple linear regression using both unadjusted and adjusted analyses revealed no association between adiposity and body composition variables with executive tasks, apart from a significant association between skeletal muscle mass (SMM) and mean reaction time on go trial (standardized B = -0.28; p = 0.02). Multivariate analysis of covariance (MANCOVA) revealed that underweight participants presented inferior working memory compared to their normal weight (p = 0.001) or overweight peers (p = 0.008). However, according to the percentage fat quartiles (Q) participants with the highest quartile (Q4) were inferior in inhibitory control than their peers with Q2 (p = 0.04), and participants with the lowest quartile (Q1) were inferior in working memory compared with their peers with Q2 (p = 0.01) or Q3 (p = 0.02). A worse inhibitory control was observed for participants with the highest fat/SMM (Q4) compared to participants in Q3 (p = 0.03), and in contrast worse working memory was observed for participants with the lowest fat/SMM (Q1) compared to participants in Q2 (p = 0.04) or Q3 (p = 0.009). Conclusions: Low adiposity is associated with worse working memory, whereas high adiposity is associated with worse inhibitory control. Therefore, our findings show that normal adiposity, but greater SMM may have a positive impact on executive function in young adults.
Original languageEnglish
Pages (from-to)363
Number of pages14
JournalMedicina
Volume55
Issue number7
DOIs
Publication statusPublished - 10 Jul 2019

Fingerprint

Executive Function
Adiposity
Short-Term Memory
Young Adult
Skeletal Muscle
Weights and Measures
Body Composition
Fats
Thinness
Neuropsychological Tests
Reaction Time
Linear Models
Multivariate Analysis

Cite this

Narimani, M., Esmaeilzadeh, S., Azevedo, L., Moradi, A., Heidari, B., & Moghadam, M. K. (2019). Association Between Weight Status and Executive Function in Young Adults. Medicina, 55(7), 363. https://doi.org/10.3390/medicina55070363
Narimani, Mohammad ; Esmaeilzadeh, Samad ; Azevedo, Liane ; Moradi, Akbar ; Heidari, Behrouz ; Moghadam, Malahat Kashfi. / Association Between Weight Status and Executive Function in Young Adults. In: Medicina. 2019 ; Vol. 55, No. 7. pp. 363.
@article{349db8601c184a9eac6f27c5c6a0da77,
title = "Association Between Weight Status and Executive Function in Young Adults",
abstract = "Background and objectives: To explore the association between weight status and executive function in young adults. Materials and Methods: Ninety-seven young males (age 17–26 years) underwent adiposity and body composition measurements using body composition analyzer. Inhibitory control and working memory were measured using the Cambridge Neuropsychological Test Battery (CANTAB). Results: Multiple linear regression using both unadjusted and adjusted analyses revealed no association between adiposity and body composition variables with executive tasks, apart from a significant association between skeletal muscle mass (SMM) and mean reaction time on go trial (standardized B = -0.28; p = 0.02). Multivariate analysis of covariance (MANCOVA) revealed that underweight participants presented inferior working memory compared to their normal weight (p = 0.001) or overweight peers (p = 0.008). However, according to the percentage fat quartiles (Q) participants with the highest quartile (Q4) were inferior in inhibitory control than their peers with Q2 (p = 0.04), and participants with the lowest quartile (Q1) were inferior in working memory compared with their peers with Q2 (p = 0.01) or Q3 (p = 0.02). A worse inhibitory control was observed for participants with the highest fat/SMM (Q4) compared to participants in Q3 (p = 0.03), and in contrast worse working memory was observed for participants with the lowest fat/SMM (Q1) compared to participants in Q2 (p = 0.04) or Q3 (p = 0.009). Conclusions: Low adiposity is associated with worse working memory, whereas high adiposity is associated with worse inhibitory control. Therefore, our findings show that normal adiposity, but greater SMM may have a positive impact on executive function in young adults.",
author = "Mohammad Narimani and Samad Esmaeilzadeh and Liane Azevedo and Akbar Moradi and Behrouz Heidari and Moghadam, {Malahat Kashfi}",
year = "2019",
month = "7",
day = "10",
doi = "10.3390/medicina55070363",
language = "English",
volume = "55",
pages = "363",
journal = "Medicina",
issn = "1010-660X",
publisher = "Kauno Medicinos Universitetas",
number = "7",

}

Narimani, M, Esmaeilzadeh, S, Azevedo, L, Moradi, A, Heidari, B & Moghadam, MK 2019, 'Association Between Weight Status and Executive Function in Young Adults', Medicina, vol. 55, no. 7, pp. 363. https://doi.org/10.3390/medicina55070363

Association Between Weight Status and Executive Function in Young Adults. / Narimani, Mohammad; Esmaeilzadeh, Samad; Azevedo, Liane; Moradi, Akbar; Heidari, Behrouz; Moghadam, Malahat Kashfi.

In: Medicina, Vol. 55, No. 7, 10.07.2019, p. 363.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Association Between Weight Status and Executive Function in Young Adults

AU - Narimani, Mohammad

AU - Esmaeilzadeh, Samad

AU - Azevedo, Liane

AU - Moradi, Akbar

AU - Heidari, Behrouz

AU - Moghadam, Malahat Kashfi

PY - 2019/7/10

Y1 - 2019/7/10

N2 - Background and objectives: To explore the association between weight status and executive function in young adults. Materials and Methods: Ninety-seven young males (age 17–26 years) underwent adiposity and body composition measurements using body composition analyzer. Inhibitory control and working memory were measured using the Cambridge Neuropsychological Test Battery (CANTAB). Results: Multiple linear regression using both unadjusted and adjusted analyses revealed no association between adiposity and body composition variables with executive tasks, apart from a significant association between skeletal muscle mass (SMM) and mean reaction time on go trial (standardized B = -0.28; p = 0.02). Multivariate analysis of covariance (MANCOVA) revealed that underweight participants presented inferior working memory compared to their normal weight (p = 0.001) or overweight peers (p = 0.008). However, according to the percentage fat quartiles (Q) participants with the highest quartile (Q4) were inferior in inhibitory control than their peers with Q2 (p = 0.04), and participants with the lowest quartile (Q1) were inferior in working memory compared with their peers with Q2 (p = 0.01) or Q3 (p = 0.02). A worse inhibitory control was observed for participants with the highest fat/SMM (Q4) compared to participants in Q3 (p = 0.03), and in contrast worse working memory was observed for participants with the lowest fat/SMM (Q1) compared to participants in Q2 (p = 0.04) or Q3 (p = 0.009). Conclusions: Low adiposity is associated with worse working memory, whereas high adiposity is associated with worse inhibitory control. Therefore, our findings show that normal adiposity, but greater SMM may have a positive impact on executive function in young adults.

AB - Background and objectives: To explore the association between weight status and executive function in young adults. Materials and Methods: Ninety-seven young males (age 17–26 years) underwent adiposity and body composition measurements using body composition analyzer. Inhibitory control and working memory were measured using the Cambridge Neuropsychological Test Battery (CANTAB). Results: Multiple linear regression using both unadjusted and adjusted analyses revealed no association between adiposity and body composition variables with executive tasks, apart from a significant association between skeletal muscle mass (SMM) and mean reaction time on go trial (standardized B = -0.28; p = 0.02). Multivariate analysis of covariance (MANCOVA) revealed that underweight participants presented inferior working memory compared to their normal weight (p = 0.001) or overweight peers (p = 0.008). However, according to the percentage fat quartiles (Q) participants with the highest quartile (Q4) were inferior in inhibitory control than their peers with Q2 (p = 0.04), and participants with the lowest quartile (Q1) were inferior in working memory compared with their peers with Q2 (p = 0.01) or Q3 (p = 0.02). A worse inhibitory control was observed for participants with the highest fat/SMM (Q4) compared to participants in Q3 (p = 0.03), and in contrast worse working memory was observed for participants with the lowest fat/SMM (Q1) compared to participants in Q2 (p = 0.04) or Q3 (p = 0.009). Conclusions: Low adiposity is associated with worse working memory, whereas high adiposity is associated with worse inhibitory control. Therefore, our findings show that normal adiposity, but greater SMM may have a positive impact on executive function in young adults.

U2 - 10.3390/medicina55070363

DO - 10.3390/medicina55070363

M3 - Article

VL - 55

SP - 363

JO - Medicina

JF - Medicina

SN - 1010-660X

IS - 7

ER -

Narimani M, Esmaeilzadeh S, Azevedo L, Moradi A, Heidari B, Moghadam MK. Association Between Weight Status and Executive Function in Young Adults. Medicina. 2019 Jul 10;55(7):363. https://doi.org/10.3390/medicina55070363