Barriers and Facilitators to Mediterranean Diet Adoption by Patients with Non-alcoholic Fatty Liver Disease in Northern Europe

Laura Haigh, Susan Bremner, David Houghton, Elsbeth Henderson, Leah Avery, Timothy Hardy, Kate Hallsworth, Stuart McPherson, Quentin Anstee

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background & Aims Dietary interventions for weight loss are effective therapies for non-alcoholic fatty liver disease (NAFLD). The Mediterranean diet might benefit these patients but it is not followed consistently in Northern European countries. We examined factors that determine Mediterranean diet adoption and maintenance in a northern European population. Methods We used a mixed-methods approach to investigate the effects of a 12-week Mediterranean diet intervention and perceived barriers and facilitators. Nineteen adults with NAFLD were recruited from a tertiary hepatology center in England. Participants were taught behavioral strategies through the provision of shopping lists, meal planners, and recipes; no advice was given on calorie allowances or physical activities. We used the 14-point Mediterranean diet assessment tool to assess dietary intake, based on a small number of foods in servings/day or servings/week, at baseline and after 12 weeks; participants were assigned scores of low (less than 5 points), moderate (6–9 points), or high (10–14 points). Semi-structured interviews were audio recorded, transcribed, and analyzed using the framework method. Results Twelve weeks after the dietary advice, Mediterranean diet adoption significantly increased from moderate to high (mean increase of 2.2 points; from 7.6+2.5 at baseline to 9.8+2.8 at 12 weeks) (P=.006). This increase was associated with a mean reduction in bodyweight of 2.4 kg (from 99.2 kg±17.0 at baseline to 96.8 kg±17.5 at 12 weeks) (P=.001) and increased serum concentrations of high-density lipoprotein cholesterol in 72% of participants (from 1.10±0.8 at baseline to 1.20±1.30 vs. 1.00±0.5 at 12 weeks) (P=.009). Increased nutrition knowledge and skills, family support, Mediterranean diet promotion in media and clinical settings, and the nutritional care facilitated diet changes. Barriers to Mediterranean diet uptake included an obesogenic environment, life stressors, and demand for convenience. Poor understanding of the causes and significance of NAFLD adversely affected readiness to change dietary habits. Conclusion In an analysis of patients with NAFLD the northern United Kingdom, we found a 12-week Mediterranean diet intervention was acceptable and associated with significant reductions in bodyweight and increased serum levels of high-density lipoprotein. We identified barriers and facilitators that could support appropriate treatment adaptations and guide personalized intervention approaches.
Original languageEnglish
Pages (from-to)1364-1371
Number of pages33
JournalClinical Gastroenterology and Hepatology
Volume17
Early online date31 Oct 2018
DOIs
Publication statusPublished - 22 May 2019

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Mediterranean Diet
Non-alcoholic Fatty Liver Disease
Feeding Behavior
Gastroenterology
HDL Lipoproteins
Serum
England
HDL Cholesterol
Meals
Weight Loss
Maintenance
Interviews
Exercise
Diet
Food

Cite this

Haigh, Laura ; Bremner, Susan ; Houghton, David ; Henderson, Elsbeth ; Avery, Leah ; Hardy, Timothy ; Hallsworth, Kate ; McPherson, Stuart ; Anstee, Quentin. / Barriers and Facilitators to Mediterranean Diet Adoption by Patients with Non-alcoholic Fatty Liver Disease in Northern Europe. In: Clinical Gastroenterology and Hepatology. 2019 ; Vol. 17. pp. 1364-1371.
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abstract = "Background & Aims Dietary interventions for weight loss are effective therapies for non-alcoholic fatty liver disease (NAFLD). The Mediterranean diet might benefit these patients but it is not followed consistently in Northern European countries. We examined factors that determine Mediterranean diet adoption and maintenance in a northern European population. Methods We used a mixed-methods approach to investigate the effects of a 12-week Mediterranean diet intervention and perceived barriers and facilitators. Nineteen adults with NAFLD were recruited from a tertiary hepatology center in England. Participants were taught behavioral strategies through the provision of shopping lists, meal planners, and recipes; no advice was given on calorie allowances or physical activities. We used the 14-point Mediterranean diet assessment tool to assess dietary intake, based on a small number of foods in servings/day or servings/week, at baseline and after 12 weeks; participants were assigned scores of low (less than 5 points), moderate (6–9 points), or high (10–14 points). Semi-structured interviews were audio recorded, transcribed, and analyzed using the framework method. Results Twelve weeks after the dietary advice, Mediterranean diet adoption significantly increased from moderate to high (mean increase of 2.2 points; from 7.6+2.5 at baseline to 9.8+2.8 at 12 weeks) (P=.006). This increase was associated with a mean reduction in bodyweight of 2.4 kg (from 99.2 kg±17.0 at baseline to 96.8 kg±17.5 at 12 weeks) (P=.001) and increased serum concentrations of high-density lipoprotein cholesterol in 72{\%} of participants (from 1.10±0.8 at baseline to 1.20±1.30 vs. 1.00±0.5 at 12 weeks) (P=.009). Increased nutrition knowledge and skills, family support, Mediterranean diet promotion in media and clinical settings, and the nutritional care facilitated diet changes. Barriers to Mediterranean diet uptake included an obesogenic environment, life stressors, and demand for convenience. Poor understanding of the causes and significance of NAFLD adversely affected readiness to change dietary habits. Conclusion In an analysis of patients with NAFLD the northern United Kingdom, we found a 12-week Mediterranean diet intervention was acceptable and associated with significant reductions in bodyweight and increased serum levels of high-density lipoprotein. We identified barriers and facilitators that could support appropriate treatment adaptations and guide personalized intervention approaches.",
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Barriers and Facilitators to Mediterranean Diet Adoption by Patients with Non-alcoholic Fatty Liver Disease in Northern Europe. / Haigh, Laura; Bremner, Susan; Houghton, David; Henderson, Elsbeth; Avery, Leah; Hardy, Timothy; Hallsworth, Kate; McPherson, Stuart; Anstee, Quentin.

In: Clinical Gastroenterology and Hepatology, Vol. 17, 22.05.2019, p. 1364-1371.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Barriers and Facilitators to Mediterranean Diet Adoption by Patients with Non-alcoholic Fatty Liver Disease in Northern Europe

AU - Haigh, Laura

AU - Bremner, Susan

AU - Houghton, David

AU - Henderson, Elsbeth

AU - Avery, Leah

AU - Hardy, Timothy

AU - Hallsworth, Kate

AU - McPherson, Stuart

AU - Anstee, Quentin

PY - 2019/5/22

Y1 - 2019/5/22

N2 - Background & Aims Dietary interventions for weight loss are effective therapies for non-alcoholic fatty liver disease (NAFLD). The Mediterranean diet might benefit these patients but it is not followed consistently in Northern European countries. We examined factors that determine Mediterranean diet adoption and maintenance in a northern European population. Methods We used a mixed-methods approach to investigate the effects of a 12-week Mediterranean diet intervention and perceived barriers and facilitators. Nineteen adults with NAFLD were recruited from a tertiary hepatology center in England. Participants were taught behavioral strategies through the provision of shopping lists, meal planners, and recipes; no advice was given on calorie allowances or physical activities. We used the 14-point Mediterranean diet assessment tool to assess dietary intake, based on a small number of foods in servings/day or servings/week, at baseline and after 12 weeks; participants were assigned scores of low (less than 5 points), moderate (6–9 points), or high (10–14 points). Semi-structured interviews were audio recorded, transcribed, and analyzed using the framework method. Results Twelve weeks after the dietary advice, Mediterranean diet adoption significantly increased from moderate to high (mean increase of 2.2 points; from 7.6+2.5 at baseline to 9.8+2.8 at 12 weeks) (P=.006). This increase was associated with a mean reduction in bodyweight of 2.4 kg (from 99.2 kg±17.0 at baseline to 96.8 kg±17.5 at 12 weeks) (P=.001) and increased serum concentrations of high-density lipoprotein cholesterol in 72% of participants (from 1.10±0.8 at baseline to 1.20±1.30 vs. 1.00±0.5 at 12 weeks) (P=.009). Increased nutrition knowledge and skills, family support, Mediterranean diet promotion in media and clinical settings, and the nutritional care facilitated diet changes. Barriers to Mediterranean diet uptake included an obesogenic environment, life stressors, and demand for convenience. Poor understanding of the causes and significance of NAFLD adversely affected readiness to change dietary habits. Conclusion In an analysis of patients with NAFLD the northern United Kingdom, we found a 12-week Mediterranean diet intervention was acceptable and associated with significant reductions in bodyweight and increased serum levels of high-density lipoprotein. We identified barriers and facilitators that could support appropriate treatment adaptations and guide personalized intervention approaches.

AB - Background & Aims Dietary interventions for weight loss are effective therapies for non-alcoholic fatty liver disease (NAFLD). The Mediterranean diet might benefit these patients but it is not followed consistently in Northern European countries. We examined factors that determine Mediterranean diet adoption and maintenance in a northern European population. Methods We used a mixed-methods approach to investigate the effects of a 12-week Mediterranean diet intervention and perceived barriers and facilitators. Nineteen adults with NAFLD were recruited from a tertiary hepatology center in England. Participants were taught behavioral strategies through the provision of shopping lists, meal planners, and recipes; no advice was given on calorie allowances or physical activities. We used the 14-point Mediterranean diet assessment tool to assess dietary intake, based on a small number of foods in servings/day or servings/week, at baseline and after 12 weeks; participants were assigned scores of low (less than 5 points), moderate (6–9 points), or high (10–14 points). Semi-structured interviews were audio recorded, transcribed, and analyzed using the framework method. Results Twelve weeks after the dietary advice, Mediterranean diet adoption significantly increased from moderate to high (mean increase of 2.2 points; from 7.6+2.5 at baseline to 9.8+2.8 at 12 weeks) (P=.006). This increase was associated with a mean reduction in bodyweight of 2.4 kg (from 99.2 kg±17.0 at baseline to 96.8 kg±17.5 at 12 weeks) (P=.001) and increased serum concentrations of high-density lipoprotein cholesterol in 72% of participants (from 1.10±0.8 at baseline to 1.20±1.30 vs. 1.00±0.5 at 12 weeks) (P=.009). Increased nutrition knowledge and skills, family support, Mediterranean diet promotion in media and clinical settings, and the nutritional care facilitated diet changes. Barriers to Mediterranean diet uptake included an obesogenic environment, life stressors, and demand for convenience. Poor understanding of the causes and significance of NAFLD adversely affected readiness to change dietary habits. Conclusion In an analysis of patients with NAFLD the northern United Kingdom, we found a 12-week Mediterranean diet intervention was acceptable and associated with significant reductions in bodyweight and increased serum levels of high-density lipoprotein. We identified barriers and facilitators that could support appropriate treatment adaptations and guide personalized intervention approaches.

U2 - 10.1016/j.cgh.2018.10.044 showArticle Info

DO - 10.1016/j.cgh.2018.10.044 showArticle Info

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JO - Clinical Gastroenterology and Hepatology

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SN - 1542-3565

ER -