BBCEAS-HLPC measurements for synthetic antioxidants (TBHQ, BHA, and BHT) in deep-UV region below 300 nm

Naser Bazina, Tariq Galadanchi Ahmed, Mostafa Almdaaf, Jibin He, Mosh Sarker, Meez Islam

Research output: Contribution to journalArticlepeer-review

Abstract

This study investigates the integration of Broadband Cavity Enhanced Absorption Spectroscopy (BBCEAS) with High-Performance Liquid Chromatography (HPLC) to detect synthetic antioxidants; BHA, BHT, and TBHQ in the deep-UV region below 300 nm. The research addresses the need for more sensitive and cost-effective detection methods in HPLC systems, particularly for low analyte concentrations, by exploring BBCEAS as a superior alternative to conventional detectors that often fall short in sensitivity. The sensitivity of the HPLC-BBCEAS system is assessed by calculating the minimum detectable change in the absorption coefficient (αmin) and comparing with those obtained using conventional HPLC and single-wavelength HPLC-CRDS methods. The findings demonstrate that the HPLC-BBCEAS system achieves αmin values of 1.8 × 10 −5 cm −1 for BHA, 2.8 × 10 −5 cm −1 for BHT, and 1.9 × 10 −5 cm −1 for TBHQ at 280 nm, with Limits of Detection (LOD) and Quantification (LOQ) up to 30 times lower than conventional HPLC systems.

Original languageEnglish
Article number142150
Number of pages8
JournalFood Chemistry
Volume465
Issue numberPart 2
Early online date19 Nov 2024
DOIs
Publication statusPublished - 15 Feb 2025

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