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Ceramides bind VDAC2 to trigger mitochondrial apoptosis
Shashank Dadsena
, Svenja Bockelmann
, John G. M. Mina
, Dina G. Hassan
, Sergei Korneev
, Guilherme Razzera
, Helene Jahn
, Patrick Niekamp
, Dagmar Müller
, Markus Schneider
, Fikadu G. Tafesse
, Siewert J. Marrink
, Manuel N. Melo
, Joost C. M. Holthuis
Centre for Biodiscovery
Research output
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Contribution to journal
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Article
›
peer-review
219
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Keyphrases
Mitochondrial Apoptosis
100%
Ceramide
100%
VDAC2
100%
Glutamate
20%
Voltage-dependent Anion Channel 1 (VDAC1)
20%
Binding Site
10%
Chemical Modification
10%
Cell Death
10%
Photoactivatable
10%
Binding Protein
10%
Head Group
10%
Induced Apoptosis
10%
Mitochondria
10%
Tumor Suppressor Lipid
10%
Voltage-dependent Anion Channel
10%
Apoptotic Cell Death
10%
Coarse-grained Molecular Dynamics Simulation
10%
Molecular Frameworks
10%
Glutamine
10%
Antineoplastic Agents
10%
Photolabeling
10%
Human Colon Cancer Cells
10%
Biochemistry, Genetics and Molecular Biology
Ceramide
100%
VDAC1
20%
Glutamic Acid
20%
Antineoplastic Activity
10%
Lipid
10%
Cancer Cell
10%
Binding Site
10%
Photoaffinity Labeling
10%
Binding Protein
10%
Mitochondrion
10%
Cell Death
10%
Tumor Suppressor Protein
10%
Apoptosis
10%
Glutamine
10%
Colon
10%
Voltage-Dependent Anion Channel
10%
Computer Simulation
10%
Neuroscience
Tumor Suppressor Protein
10%