Multi-axial creep damage constitutive equations are developed for 0.5Cr0.5Mo0.25V ferritic steel at 590°C. It is aimed to overcome the deficiency of inconsistency in predicted and observed creep strains existed in previous formulations [Q. Xu, in: European Conference on Advances in Mechanical Behaviour, Plasticity and Damage, 7–9 November 2000, Tours, France; Creep Damage Mechanics Research Report, The School of Engineering, The University of Huddersfield, 2000; I.J. Perrin, D.R. Hayhurst, J. Strain Anal. 31 (4) (1996) 299]. In this paper, the lifetime and strain at failure are qualitatively validated in a wider range of states of stress by which the capability of producing consistent results is demonstrated.