Educational platform trials simulator (EPTS): Software for planning and simulating cluster-randomised, multisite and simple randomised platform trials

Mohammad  Sayari; Akansha  Singh; Germaine  Uwimpuhwe; Nasima Akhter; Tahani  Coolen-Maturi; Rashmika Gupta; Jochen Einbeck

doi:10.1016/j.softx.2025.102214

Educational platform trials simulator (EPTS): Software for planning and simulating cluster-randomised, multisite and simple randomised platform trials

Mohammad Sayari
, Akansha Singh
, Germaine Uwimpuhwe
, Nasima Akhter
, Tahani Coolen-Maturi
, Rashmika Gupta
, Jochen Einbeck

Research output: Contribution to journal › Article › peer-review

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Abstract

Platform trials offer a robust framework for evaluating multiple interventions simultaneously against a common control group within a single master protocol. Acknowledging their increased importance in the medical and social sciences, including education, a specialised software ‘Educational Platform Trials Simulator (EPTS) is designed. The software's user-friendly interface allows users to plan and execute simulations for randomised controlled trial designs, analyse data (Bayesian/ Frequentist methods, multilevel models, futility and superiority analyses), and visualise results without requiring extensive programming expertise. This practical, economical and academic tool facilitates efficient and effective research involving planning and simulating platform trials in education and other disciplines.

Original language	English
Article number	102214
Number of pages	8
Journal	SoftwareX
Volume	31
Early online date	30 May 2025
DOIs	https://doi.org/10.1016/j.softx.2025.102214
Publication status	Published - 1 Sept 2025

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abstract = "Platform trials offer a robust framework for evaluating multiple interventions simultaneously against a common control group within a single master protocol. Acknowledging their increased importance in the medical and social sciences, including education, a specialised software {\textquoteleft}Educational Platform Trials Simulator (EPTS) is designed. The software's user-friendly interface allows users to plan and execute simulations for randomised controlled trial designs, analyse data (Bayesian/ Frequentist methods, multilevel models, futility and superiority analyses), and visualise results without requiring extensive programming expertise. This practical, economical and academic tool facilitates efficient and effective research involving planning and simulating platform trials in education and other disciplines.",

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AU - Sayari, Mohammad

AU - Singh, Akansha

AU - Uwimpuhwe, Germaine

AU - Akhter, Nasima

AU - Coolen-Maturi, Tahani

AU - Gupta, Rashmika

AU - Einbeck, Jochen

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AB - Platform trials offer a robust framework for evaluating multiple interventions simultaneously against a common control group within a single master protocol. Acknowledging their increased importance in the medical and social sciences, including education, a specialised software ‘Educational Platform Trials Simulator (EPTS) is designed. The software's user-friendly interface allows users to plan and execute simulations for randomised controlled trial designs, analyse data (Bayesian/ Frequentist methods, multilevel models, futility and superiority analyses), and visualise results without requiring extensive programming expertise. This practical, economical and academic tool facilitates efficient and effective research involving planning and simulating platform trials in education and other disciplines.

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JO - SoftwareX

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M1 - 102214

ER -

Educational platform trials simulator (EPTS): Software for planning and simulating cluster-randomised, multisite and simple randomised platform trials

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