Oxygen (O2) enriched air combustion via adaption of polymeric membranes has been proposed to be a feasible alternative to increase combustion proficiency while minimizing the emission of greenhouse gases into the atmosphere. Nonetheless, majority of techno-economic assessment on the O2 enriched combustion evolving membrane separation process are confined to assumption of constant membrane permeance. In reality, it is well known that membrane permeance is highly dependent upon the temperature and pressure to which it is operated. Therefore, in this work, an empirical model, which includes the effect of temperature and pressure to permeance, has been evaluated based on own experimental work using polysulfone membrane. The empirical model has been further validated with published experimental results. It is found that the model is able to provide an excellent characterization of the membrane permeance across a wide range of operating conditions for both pure and binary gas with determination coefficient of minimally 0.99.