Experimental and In Silico Modelling Analyses of the Gene Expression Pathway for Recombinant Antibody and By-Product Production in NS0 Cell Lines

Keyphrases

• Modeling Analysis 100%
• In Silico Modeling 100%
• Gene Pathway 100%
• NS0 Cells 100%
• Recombinant Antibody 100%
• Antibody Expression 100%
• Drug Use 33%
• Recombinant Protein Production 33%
• Monoclonal Antibody 33%
• Disulfide Bond 33%
• Secretion Rate 33%
• Recombinant Protein 33%
• Quaternary Structure 33%
• Polypeptide 33%
• Expression Level 33%
• Biological Mechanisms 33%
• IgG4-related Disease (IgG4-RD) 33%
• Secretory Machinery 33%
• Species Level 33%
• Complex Molecules 33%
• Experimental Strategies 33%
• Light Chain 33%
• Intrinsically Linked 33%
• Commercially Important 33%
• Heavy Chain 33%
• Recombinant Cells 33%
• Product Heterogeneity 33%
• Modeling Strategy 33%
• Nonlinear Model 33%
• Biotherapeutics 33%
• Polypeptide Chain 33%
• Cultured Mammalian Cells 33%
• Precursor Species 33%

Immunology and Microbiology

• Gene Expression 100%
• Cell Line 100%
• Recombinant Antibody 100%
• NS0 Cell Line 100%
• Monoclonal Antibody 25%
• Secretion (Process) 25%
• Precursor 25%
• Light Chain 25%
• Heavy Chain 25%
• Disulfide Bond 25%
• Immunoglobulin G4 25%
• Protein Quaternary Structure 25%

Biochemistry, Genetics and Molecular Biology

• Gene Expression 100%
• Recombinant Protein 100%
• Monoclonal Antibody 50%
• Secretion (Process) 50%
• Precursor 50%
• Protein Quaternary Structure 50%
• Heavy Chain 50%
• Disulfide Bond 50%
• Light Chain 50%
• Expression Level 50%