Feasibility of a digital behaviour change intervention (VITALISE) for adults with non-alcoholic fatty liver disease.

Hollie Smith, Kate Hallsworth, Stuart McPherson, Leah Avery

Research output: Contribution to conferencePosterpeer-review


Non-alcoholic fatty liver disease (NAFLD), a disease predominantly linked to overweight and obesity, affects 25% of adults in Western countries. Lifestyle behaviour change to initiate weight loss is the recommended management approach. However, patients find weight loss challenging. Using intervention mapping, we developed a NAFLD-specific digital behaviour change intervention (VITALISE) with tele-coaching support to target changes in dietary and physical activity behaviours. This study will assess the feasibility and acceptability of VITALISE in a secondary care setting.

We aim to recruit thirty-five newly diagnosed patients with NAFLD who will be given access to VITALISE for 6 months. A single-centre, one-arm prospective study design will assess feasibility, acceptability and fidelity of the intervention, recruitment, retention, uptake, engagement, and adherence. Qualitative interviews will inform intervention optimisation. Secondary outcomes include liver health (routine blood tests and FibroScan), physical activity (Godin Leisure-Time Exercise Questionnaire and accelerometery) and patient activation (Patient Activation Measure).

Expected results
Early indications demonstrate recruitment and data collection is feasible, and acceptability of the intervention is good (i.e., engagement is consistent).

Current stage of work
18 patients (male n=14) from White British (n=16), Hispanic (n=1) and British Asian (n=1) backgrounds (mean age 56 years; SD=11.68) have been recruited. Eleven patients have engaged with VITALISE, including three who have engaged with tele-coaching.

This study will determine the feasibility and acceptability of a digital behaviour change intervention (VITALISE) that aims to facilitate guideline implementation in clinical settings for people with NAFLD. Findings will inform intervention optimisation and larger scale evaluation.
Original languageEnglish
Publication statusPublished - 4 Sept 2023
EventEuropean Health Psychology Society Conference: EHPS 2023 - University of Bremen, Bremen, Germany
Duration: 4 Sept 20238 Oct 2023


ConferenceEuropean Health Psychology Society Conference: EHPS 2023
Internet address


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