Filipins: The first antifungal "weed killers" identified from bacteria isolated from the trap-ant

Hong Gao; Sabine Grüschow; Jörg Barke; Ryan F. Seipke; Lionel M. Hill; Jérôme Orivel; Douglas W. Yu; Matthew Hutchings; Rebecca J.M. Goss

doi:10.1039/c4ra09875g

Filipins: The first antifungal "weed killers" identified from bacteria isolated from the trap-ant

Hong Gao, Sabine Grüschow, Jörg Barke, Ryan F. Seipke, Lionel M. Hill, Jérôme Orivel, Douglas W. Yu, Matthew Hutchings, Rebecca J.M. Goss

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Allomerus ants ensure that they have sufficient nitrogen in their diet by trapping and consuming other insects. In order to construct their traps, like the more extensively studied leaf cutter ants, they employ fungal farming. Pest management within these fungal cultures has been speculated to be due to the ants' usage of actinomycetes capable of producing antifungal compounds, analogous to the leafcutter ant mutualism. Here we report the first identification of a series of antifungal compounds, the filipins, and their associated biosynthetic genes isolated from a bacterium associated with this system.

Original language	English
Pages (from-to)	57267-57270
Number of pages	4
Journal	RSC Advances
Volume	4
Issue number	100
DOIs	https://doi.org/10.1039/c4ra09875g
Publication status	Published - 1 Jan 2014

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10.1039/c4ra09875g

https://pubs.rsc.org/en/content/articlelanding/2014/ra/c4ra09875g#!divAbstract

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title = "Filipins: The first antifungal {"}weed killers{"} identified from bacteria isolated from the trap-ant",

abstract = "Allomerus ants ensure that they have sufficient nitrogen in their diet by trapping and consuming other insects. In order to construct their traps, like the more extensively studied leaf cutter ants, they employ fungal farming. Pest management within these fungal cultures has been speculated to be due to the ants' usage of actinomycetes capable of producing antifungal compounds, analogous to the leafcutter ant mutualism. Here we report the first identification of a series of antifungal compounds, the filipins, and their associated biosynthetic genes isolated from a bacterium associated with this system.",

author = "Hong Gao and Sabine Gr{\"u}schow and J{\"o}rg Barke and Seipke, {Ryan F.} and Hill, {Lionel M.} and J{\'e}r{\^o}me Orivel and Yu, {Douglas W.} and Matthew Hutchings and Goss, {Rebecca J.M.}",

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AU - Gao, Hong

AU - Grüschow, Sabine

AU - Barke, Jörg

AU - Seipke, Ryan F.

AU - Hill, Lionel M.

AU - Orivel, Jérôme

AU - Yu, Douglas W.

AU - Hutchings, Matthew

AU - Goss, Rebecca J.M.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Allomerus ants ensure that they have sufficient nitrogen in their diet by trapping and consuming other insects. In order to construct their traps, like the more extensively studied leaf cutter ants, they employ fungal farming. Pest management within these fungal cultures has been speculated to be due to the ants' usage of actinomycetes capable of producing antifungal compounds, analogous to the leafcutter ant mutualism. Here we report the first identification of a series of antifungal compounds, the filipins, and their associated biosynthetic genes isolated from a bacterium associated with this system.

AB - Allomerus ants ensure that they have sufficient nitrogen in their diet by trapping and consuming other insects. In order to construct their traps, like the more extensively studied leaf cutter ants, they employ fungal farming. Pest management within these fungal cultures has been speculated to be due to the ants' usage of actinomycetes capable of producing antifungal compounds, analogous to the leafcutter ant mutualism. Here we report the first identification of a series of antifungal compounds, the filipins, and their associated biosynthetic genes isolated from a bacterium associated with this system.

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DO - 10.1039/c4ra09875g

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SP - 57267

EP - 57270

JO - RSC Advances

JF - RSC Advances

IS - 100

ER -

Filipins: The first antifungal "weed killers" identified from bacteria isolated from the trap-ant

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Filipins: The first antifungal "weed killers" identified from bacteria isolated from the trap-ant

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