Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management

Ahmad Alkhatib, Catherine Tsang, Ali Tiss, Theeshan Bahorun, Hossein Arefanian, Roula Barake, Abdelkrim Khadir, Jaakko Tuomilehto

Research output: Contribution to journalReview article

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Abstract

Functional foods contain biologically active ingredients associated with physiological health benefits for preventing and managing chronic diseases, such as type 2 diabetes mellitus (T2DM). A regular consumption of functional foods may be associated with enhanced anti-oxidant, anti-inflammatory, insulin sensitivity, and anti-cholesterol functions, which are considered integral to prevent and manage T2DM. Components of the Mediterranean diet (MD)-such as fruits, vegetables, oily fish, olive oil, and tree nuts-serve as a model for functional foods based on their natural contents of nutraceuticals, including polyphenols, terpenoids, flavonoids, alkaloids, sterols, pigments, and unsaturated fatty acids. Polyphenols within MD and polyphenol-rich herbs-such as coffee, green tea, black tea, and yerba maté-have shown clinically-meaningful benefits on metabolic and microvascular activities, cholesterol and fasting glucose lowering, and anti-inflammation and anti-oxidation in high-risk and T2DM patients. However, combining exercise with functional food consumption can trigger and augment several metabolic and cardiovascular protective benefits, but it is under-investigated in people with T2DM and bariatric surgery patients. Detecting functional food benefits can now rely on an "omics" biological profiling of individuals' molecular, genetics, transcriptomics, proteomics, and metabolomics, but is under-investigated in multi-component interventions. A personalized approach for preventing and managing T2DM should consider biological and behavioral models, and embed nutrition education as part of lifestyle diabetes prevention studies. Functional foods may provide additional benefits in such an approach.

Original languageEnglish
JournalNutrients
Volume9
Issue number12
DOIs
Publication statusPublished - 1 Dec 2017

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Functional Food
functional foods
lifestyle
diabetes
Life Style
Type 2 Diabetes Mellitus
noninsulin-dependent diabetes mellitus
Polyphenols
Mediterranean Diet
polyphenols
Mediterranean diet
Tea
Cholesterol
Biological Models
cholesterol
Nuts
Metabolomics
Bariatric Surgery
Fish Oils
bariatric surgery

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Alkhatib, A., Tsang, C., Tiss, A., Bahorun, T., Arefanian, H., Barake, R., ... Tuomilehto, J. (2017). Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management. Nutrients, 9(12). https://doi.org/10.3390/nu9121310
Alkhatib, Ahmad ; Tsang, Catherine ; Tiss, Ali ; Bahorun, Theeshan ; Arefanian, Hossein ; Barake, Roula ; Khadir, Abdelkrim ; Tuomilehto, Jaakko. / Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management. In: Nutrients. 2017 ; Vol. 9, No. 12.
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Alkhatib, A, Tsang, C, Tiss, A, Bahorun, T, Arefanian, H, Barake, R, Khadir, A & Tuomilehto, J 2017, 'Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management', Nutrients, vol. 9, no. 12. https://doi.org/10.3390/nu9121310

Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management. / Alkhatib, Ahmad; Tsang, Catherine; Tiss, Ali; Bahorun, Theeshan; Arefanian, Hossein; Barake, Roula; Khadir, Abdelkrim; Tuomilehto, Jaakko.

In: Nutrients, Vol. 9, No. 12, 01.12.2017.

Research output: Contribution to journalReview article

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T1 - Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management

AU - Alkhatib, Ahmad

AU - Tsang, Catherine

AU - Tiss, Ali

AU - Bahorun, Theeshan

AU - Arefanian, Hossein

AU - Barake, Roula

AU - Khadir, Abdelkrim

AU - Tuomilehto, Jaakko

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Functional foods contain biologically active ingredients associated with physiological health benefits for preventing and managing chronic diseases, such as type 2 diabetes mellitus (T2DM). A regular consumption of functional foods may be associated with enhanced anti-oxidant, anti-inflammatory, insulin sensitivity, and anti-cholesterol functions, which are considered integral to prevent and manage T2DM. Components of the Mediterranean diet (MD)-such as fruits, vegetables, oily fish, olive oil, and tree nuts-serve as a model for functional foods based on their natural contents of nutraceuticals, including polyphenols, terpenoids, flavonoids, alkaloids, sterols, pigments, and unsaturated fatty acids. Polyphenols within MD and polyphenol-rich herbs-such as coffee, green tea, black tea, and yerba maté-have shown clinically-meaningful benefits on metabolic and microvascular activities, cholesterol and fasting glucose lowering, and anti-inflammation and anti-oxidation in high-risk and T2DM patients. However, combining exercise with functional food consumption can trigger and augment several metabolic and cardiovascular protective benefits, but it is under-investigated in people with T2DM and bariatric surgery patients. Detecting functional food benefits can now rely on an "omics" biological profiling of individuals' molecular, genetics, transcriptomics, proteomics, and metabolomics, but is under-investigated in multi-component interventions. A personalized approach for preventing and managing T2DM should consider biological and behavioral models, and embed nutrition education as part of lifestyle diabetes prevention studies. Functional foods may provide additional benefits in such an approach.

AB - Functional foods contain biologically active ingredients associated with physiological health benefits for preventing and managing chronic diseases, such as type 2 diabetes mellitus (T2DM). A regular consumption of functional foods may be associated with enhanced anti-oxidant, anti-inflammatory, insulin sensitivity, and anti-cholesterol functions, which are considered integral to prevent and manage T2DM. Components of the Mediterranean diet (MD)-such as fruits, vegetables, oily fish, olive oil, and tree nuts-serve as a model for functional foods based on their natural contents of nutraceuticals, including polyphenols, terpenoids, flavonoids, alkaloids, sterols, pigments, and unsaturated fatty acids. Polyphenols within MD and polyphenol-rich herbs-such as coffee, green tea, black tea, and yerba maté-have shown clinically-meaningful benefits on metabolic and microvascular activities, cholesterol and fasting glucose lowering, and anti-inflammation and anti-oxidation in high-risk and T2DM patients. However, combining exercise with functional food consumption can trigger and augment several metabolic and cardiovascular protective benefits, but it is under-investigated in people with T2DM and bariatric surgery patients. Detecting functional food benefits can now rely on an "omics" biological profiling of individuals' molecular, genetics, transcriptomics, proteomics, and metabolomics, but is under-investigated in multi-component interventions. A personalized approach for preventing and managing T2DM should consider biological and behavioral models, and embed nutrition education as part of lifestyle diabetes prevention studies. Functional foods may provide additional benefits in such an approach.

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C2 - 29194424

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JO - Nutrients

JF - Nutrients

SN - 2072-6643

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ER -