@inbook{7509411d66b942a8b35c2a75b4664518,
title = "Future directions and challenges involved in cancer noncoding RNomics",
abstract = "Recent advances in high-throughput technologies have revealed that a large proportion (∼70%) of the human genome transcribes into RNAs, which highlights the importance of the noncoding genome. However, the annotation and functional characterization of these transcripts are yet to be explored. Although the experimental protocols and the computational tools have been constantly evolving to better understand the biology of the noncoding genome, such methods still require significant improvement for their functional characterization. This chapter discusses the future perspectives in understanding noncoding RNA biology and the various challenges faced in the interpretation of their primary sequences, structure, and functions. Existing literature portrays noncoding transcripts as highly stable, functionally diverse, and important regulators of several cellular processes. Expanding knowledge in this field will not only help in understanding the complex diseases such as cancer but also help identify biomarkers for disease development and response to therapy.",
author = "{Sharma Saha}, Sweta and Sharmila Sengupta",
year = "2017",
month = oct,
day = "2",
doi = "10.1016/B978-0-12-811022-5.00028-0",
language = "English",
isbn = "9780128110225",
volume = "1",
series = "Translational Epigenetics",
publisher = "Academic Press",
pages = "509--524",
editor = "Trygve Tollefsbol and Jayprokas Chakrabarti and Sanga Mitra",
booktitle = "Cancer and Noncoding RNAs",
address = "United Kingdom",
edition = "1",
}