Genome wide molecular characterisation of central nervous system primative neuroectodermal tumour and pineoblastoma

Beth Coyle, Richard G Grundy, Suzanne Miller, Hazel A Rogers, Paul Lyon, Vikki Rand, Martyna Adamowicz-Brice, Steven C Clifford, James T Hayden, Sara Dyer, Stefan Pfister, Andrey Korshunov, Marie-Anne Brundler, James Lowe

    Research output: Contribution to journalMeeting Abstract

    Abstract

    CNS PNET and pineoblastoma are highly malignant embryonal brain tumours of poor prognosis. Current therapies are based on the treatment of paediatric medulloblastoma, even though these tumours are distinct at both the anatomical and molecular level. CNS PNET and pineoblastoma have a worse clinical outcome than medulloblastoma, thus improved therapies based on an understanding of the underlying biology of CNS PNET and pineoblastoma are needed.
    Original languageEnglish
    Number of pages1
    JournalNeuro-Oncology
    Volume13
    Issue numbersupplement 2
    DOIs
    Publication statusPublished - 1 Oct 2011
    Event2011 BNOS Conference - Homerton College, Cambridge, United Kingdom
    Duration: 29 Jun 20111 Jul 2011

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    Coyle, B., Grundy, R. G., Miller, S., Rogers, H. A., Lyon, P., Rand, V., Adamowicz-Brice, M., Clifford, S. C., Hayden, J. T., Dyer, S., Pfister, S., Korshunov, A., Brundler, M-A., & Lowe, J. (2011). Genome wide molecular characterisation of central nervous system primative neuroectodermal tumour and pineoblastoma. Neuro-Oncology, 13(supplement 2). https://doi.org/10.1093/neuonc/nor144