Glycemic control in Kuwaiti diabetes patients treated with glucose-lowering medication

Ameera Abdullah, Abdullah Alkandari, Joseph C. Longenecker, Sriraman Devarajan, Ahmad Alkhatib, Rihab Al-wotayan, Qais Al-duwairi, Jaakko Tuomilehto

Research output: Contribution to journalArticle

Abstract

Background: Diabetes is prevalent in Kuwait. We aimed to assess the level of glycemic control in Kuwaiti adults with diabetes. Methods: The World Health Organization's STEPS non-communicable disease risk factor survey was conducted in Kuwait in 2014. Participants’ demographics, medical history, physical measurements and blood biochemistry were assessed. A total of 2561 Kuwaiti men and women aged 18–69 years completed all three survey steps. Glycemic control in 278 individuals with diabetes who were on glucose-lowering medication was determined using the US National Institutes of Health guidelines of fasting plasma glucose (FPG) ≤7.2 mmol/l and the American Diabetes Association guidelines of glycated hemoglobin (HbA1c) <7% (53 mmol/mol). Results: Adequate glycemic control in people with drug-treated diabetes was 34.5% when determined by HbA1c, 37.8% when determined by FPG level, and 24.5% when both criteria were met. Mean body-mass index and fasting serum triglycerides were significantly higher and serum high-density lipoprotein-cholesterol significantly lower in individuals with an inadequate glycemic control than in those with adequate control. Women with diabetes were almost twice as likely to have inadequate HbA1c levels as men with diabetes (OR, 1.9, [95% CI, 1.03, 3.5]). Conclusions: Glycemic control in Kuwaiti adults with treated diabetes is low. A systemic, multi-disciplinary public health approach is needed to improve diabetes education and adherence to treatment.

Original languageEnglish
JournalPrimary Care Diabetes
DOIs
Publication statusPublished - 5 Jan 2020

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Kuwait
Fasting
Glucose
Guidelines
National Institutes of Health (U.S.)
Glycosylated Hemoglobin A
Serum
Biochemistry
HDL Cholesterol
Triglycerides
Body Mass Index
Public Health
Demography
Education
Pharmaceutical Preparations
Surveys and Questionnaires
Therapeutics

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Abdullah, A., Alkandari, A., Longenecker, J. C., Devarajan, S., Alkhatib, A., Al-wotayan, R., ... Tuomilehto, J. (2020). Glycemic control in Kuwaiti diabetes patients treated with glucose-lowering medication. Primary Care Diabetes. https://doi.org/10.1016/j.pcd.2019.12.001
Abdullah, Ameera ; Alkandari, Abdullah ; Longenecker, Joseph C. ; Devarajan, Sriraman ; Alkhatib, Ahmad ; Al-wotayan, Rihab ; Al-duwairi, Qais ; Tuomilehto, Jaakko. / Glycemic control in Kuwaiti diabetes patients treated with glucose-lowering medication. In: Primary Care Diabetes. 2020.
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abstract = "Background: Diabetes is prevalent in Kuwait. We aimed to assess the level of glycemic control in Kuwaiti adults with diabetes. Methods: The World Health Organization's STEPS non-communicable disease risk factor survey was conducted in Kuwait in 2014. Participants’ demographics, medical history, physical measurements and blood biochemistry were assessed. A total of 2561 Kuwaiti men and women aged 18–69 years completed all three survey steps. Glycemic control in 278 individuals with diabetes who were on glucose-lowering medication was determined using the US National Institutes of Health guidelines of fasting plasma glucose (FPG) ≤7.2 mmol/l and the American Diabetes Association guidelines of glycated hemoglobin (HbA1c) <7{\%} (53 mmol/mol). Results: Adequate glycemic control in people with drug-treated diabetes was 34.5{\%} when determined by HbA1c, 37.8{\%} when determined by FPG level, and 24.5{\%} when both criteria were met. Mean body-mass index and fasting serum triglycerides were significantly higher and serum high-density lipoprotein-cholesterol significantly lower in individuals with an inadequate glycemic control than in those with adequate control. Women with diabetes were almost twice as likely to have inadequate HbA1c levels as men with diabetes (OR, 1.9, [95{\%} CI, 1.03, 3.5]). Conclusions: Glycemic control in Kuwaiti adults with treated diabetes is low. A systemic, multi-disciplinary public health approach is needed to improve diabetes education and adherence to treatment.",
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Abdullah, A, Alkandari, A, Longenecker, JC, Devarajan, S, Alkhatib, A, Al-wotayan, R, Al-duwairi, Q & Tuomilehto, J 2020, 'Glycemic control in Kuwaiti diabetes patients treated with glucose-lowering medication', Primary Care Diabetes. https://doi.org/10.1016/j.pcd.2019.12.001

Glycemic control in Kuwaiti diabetes patients treated with glucose-lowering medication. / Abdullah, Ameera; Alkandari, Abdullah; Longenecker, Joseph C.; Devarajan, Sriraman; Alkhatib, Ahmad; Al-wotayan, Rihab; Al-duwairi, Qais; Tuomilehto, Jaakko.

In: Primary Care Diabetes, 05.01.2020.

Research output: Contribution to journalArticle

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T1 - Glycemic control in Kuwaiti diabetes patients treated with glucose-lowering medication

AU - Abdullah, Ameera

AU - Alkandari, Abdullah

AU - Longenecker, Joseph C.

AU - Devarajan, Sriraman

AU - Alkhatib, Ahmad

AU - Al-wotayan, Rihab

AU - Al-duwairi, Qais

AU - Tuomilehto, Jaakko

PY - 2020/1/5

Y1 - 2020/1/5

N2 - Background: Diabetes is prevalent in Kuwait. We aimed to assess the level of glycemic control in Kuwaiti adults with diabetes. Methods: The World Health Organization's STEPS non-communicable disease risk factor survey was conducted in Kuwait in 2014. Participants’ demographics, medical history, physical measurements and blood biochemistry were assessed. A total of 2561 Kuwaiti men and women aged 18–69 years completed all three survey steps. Glycemic control in 278 individuals with diabetes who were on glucose-lowering medication was determined using the US National Institutes of Health guidelines of fasting plasma glucose (FPG) ≤7.2 mmol/l and the American Diabetes Association guidelines of glycated hemoglobin (HbA1c) <7% (53 mmol/mol). Results: Adequate glycemic control in people with drug-treated diabetes was 34.5% when determined by HbA1c, 37.8% when determined by FPG level, and 24.5% when both criteria were met. Mean body-mass index and fasting serum triglycerides were significantly higher and serum high-density lipoprotein-cholesterol significantly lower in individuals with an inadequate glycemic control than in those with adequate control. Women with diabetes were almost twice as likely to have inadequate HbA1c levels as men with diabetes (OR, 1.9, [95% CI, 1.03, 3.5]). Conclusions: Glycemic control in Kuwaiti adults with treated diabetes is low. A systemic, multi-disciplinary public health approach is needed to improve diabetes education and adherence to treatment.

AB - Background: Diabetes is prevalent in Kuwait. We aimed to assess the level of glycemic control in Kuwaiti adults with diabetes. Methods: The World Health Organization's STEPS non-communicable disease risk factor survey was conducted in Kuwait in 2014. Participants’ demographics, medical history, physical measurements and blood biochemistry were assessed. A total of 2561 Kuwaiti men and women aged 18–69 years completed all three survey steps. Glycemic control in 278 individuals with diabetes who were on glucose-lowering medication was determined using the US National Institutes of Health guidelines of fasting plasma glucose (FPG) ≤7.2 mmol/l and the American Diabetes Association guidelines of glycated hemoglobin (HbA1c) <7% (53 mmol/mol). Results: Adequate glycemic control in people with drug-treated diabetes was 34.5% when determined by HbA1c, 37.8% when determined by FPG level, and 24.5% when both criteria were met. Mean body-mass index and fasting serum triglycerides were significantly higher and serum high-density lipoprotein-cholesterol significantly lower in individuals with an inadequate glycemic control than in those with adequate control. Women with diabetes were almost twice as likely to have inadequate HbA1c levels as men with diabetes (OR, 1.9, [95% CI, 1.03, 3.5]). Conclusions: Glycemic control in Kuwaiti adults with treated diabetes is low. A systemic, multi-disciplinary public health approach is needed to improve diabetes education and adherence to treatment.

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SN - 1751-9918

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