High-resolution copy number analysis using low input, degraded DNA from fine-needle aspirates and macrodissected archival Burkitt lymphoma material

Peixun Zhou, Rachel Crossland, Amy Erhorn, Vikki Rand

Research output: Contribution to journalMeeting Abstractpeer-review

Abstract

High cure rates are now achieved for children diag-
nosed with Burkitt lymphoma (BL) in the western world, however
outcome for children who do not respond to therapy remains dire.
Moreover, only 48% of children are cured by front-line therapies in
resource-constrained countries such as Malawi. Although there is a
clear need to understand the underlying biology of these hard-to-
treat BLs, material is often limited and the required amount of DNA
for genomic analysis is often not attainable. It is therefore important
to identify methods to ensure we can analyse the genomes of these
patients
Original languageEnglish
Pages (from-to)62-62
JournalBritish Journal of Haematology
DOIs
Publication statusPublished - 4 Oct 2015
EventFifth International Symposium on Childhood Adolescent and Young Adult Non-Hodgkin Lymphoma - Varase, Italy
Duration: 22 Oct 201524 Oct 2015
https://onlinelibrary.wiley.com/doi/abs/10.1111/bjh.13753

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