Abstract
Unlike many other childhood cancers, genomic abnor-
malities are not used in the clinical management of paediatric Bur-
kitt lymphoma (BL) and few prognostic biomarkers have been
identified. In sporadic BL gain of chromosome 7 and deletion of 13q
are the only abnormalities that have been associated with an adverse
prognosis in the context of a clinical trial. Gains of 13q have also
been reported, including gain of the miR17HG locus, but the prog-
nostic value in endemic BL is unknown
malities are not used in the clinical management of paediatric Bur-
kitt lymphoma (BL) and few prognostic biomarkers have been
identified. In sporadic BL gain of chromosome 7 and deletion of 13q
are the only abnormalities that have been associated with an adverse
prognosis in the context of a clinical trial. Gains of 13q have also
been reported, including gain of the miR17HG locus, but the prog-
nostic value in endemic BL is unknown
Original language | English |
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Pages (from-to) | 2-2 |
Journal | British Journal of Haematology |
Volume | 171 |
Issue number | Suppl 1 |
Publication status | Published - 4 Oct 2015 |
Event | Fifth International Symposium on Childhood Adolescent and Young Adult Non-Hodgkin Lymphoma - Varase, Italy Duration: 22 Oct 2015 → 24 Oct 2015 https://onlinelibrary.wiley.com/doi/abs/10.1111/bjh.13753 |