Meningioma and mood: exploring the potential for meningioma to affect psychological distress before and after surgical removal

Tamsin Williams, Donald Brechin, Steven Muncer, Nitin Mukerji, Stephen Evans, Natasha Anderson

Research output: Contribution to journalArticle

Abstract

Background: Much of the research exploring psychological distress with meningioma stem from studies including several brain tumour types (including malignant tumours) meaning that focus on meningioma is limited and that conclusions are based on small samples. Moreover, contradictory findings have been reported regarding the effects of meningioma on mood. Here, the authors present a study exploring pre and post mood scores in meningioma only patients using a sample size larger than any previous research attempt.

Method: The Hospital Anxiety and Depression Scale (HADS) was used as an objective measure of mood in a clinical sample of 184 UK patients pre and post meningioma removal surgery. Repeated measures designs were used to assess for significant differences in depression and anxiety scores before and after surgery, chi-squared analyses were used to establish for clinically significant change.

Results: The study revealed a significant decrease, and a medium effect size, in mean depression scores after surgery to remove the meningioma (p = .002, g = 0.35). However, no significant effect was found following meningioma removal and anxiety scores (p = .113, g = 0.17).

Discussion: No significant effects were determined between mood and meningioma location. A discussion of the findings, and potential implications, is presented.
Original languageEnglish
Pages (from-to)383-387
Number of pages5
JournalBritish Journal of Neurosurgery
Volume33
Issue number4
Early online date4 Mar 2019
DOIs
Publication statusPublished - 3 Apr 2019

Fingerprint Dive into the research topics of 'Meningioma and mood: exploring the potential for meningioma to affect psychological distress before and after surgical removal'. Together they form a unique fingerprint.

  • Cite this