TY - JOUR
T1 - Nanocellulose Extraction from Biomass Waste
T2 - Unlocking Sustainable Pathways for Biomedical Applications
AU - Ghamari, Mehrdad
AU - Suvish, null
AU - Hwang See, Chan
AU - Yu, Hongnian
AU - Anitha, Thiyagarajan
AU - Balamurugan, V.T.
AU - Velusamy, Sasireka
AU - Hughes, David
AU - Sundaram, Senthilarasu
PY - 2025/3/4
Y1 - 2025/3/4
N2 - The escalating global waste crisis necessitates innovative solutions. This study investigates the sustainable production of nanocellulose from biomass waste and its biomedical applications. Cellulose-rich materials-including wood, textiles, agricultural residues, and food by-products-were systematically processed using alkaline, acid, and oxidative pretreatments to enhance fiber accessibility. Mechanical techniques, such as grinding and homogenization, combined with chemical methods like acid hydrolysis and 2,2,6,6-Tetramethylpiperidin-1-yl-oxyl (TEMPO) oxidation, were employed to successfully isolate nanocellulose. Post-treatment modifications, including surface coating and cross-linking, further tailored its properties for specific applications. The results demonstrated nanocellulose's biocompatibility, biodegradability, and functional versatility. In wound healing, it enhanced moisture management and exhibited antimicrobial properties. Its high surface area facilitated efficient drug loading and controlled release in drug delivery applications. Nanocellulose bioinks supported cell proliferation in 3D bioprinting for tissue engineering. Additional applications in biosensors and personal care products were also identified. This study advances sustainable materials science, aligning resource conservation with circular economy principles to address biomedical sector needs. [Abstract copyright: © 2025 The Author(s). The Chemical Record published by The Chemical Society of Japan and Wiley-VCH GmbH.]
AB - The escalating global waste crisis necessitates innovative solutions. This study investigates the sustainable production of nanocellulose from biomass waste and its biomedical applications. Cellulose-rich materials-including wood, textiles, agricultural residues, and food by-products-were systematically processed using alkaline, acid, and oxidative pretreatments to enhance fiber accessibility. Mechanical techniques, such as grinding and homogenization, combined with chemical methods like acid hydrolysis and 2,2,6,6-Tetramethylpiperidin-1-yl-oxyl (TEMPO) oxidation, were employed to successfully isolate nanocellulose. Post-treatment modifications, including surface coating and cross-linking, further tailored its properties for specific applications. The results demonstrated nanocellulose's biocompatibility, biodegradability, and functional versatility. In wound healing, it enhanced moisture management and exhibited antimicrobial properties. Its high surface area facilitated efficient drug loading and controlled release in drug delivery applications. Nanocellulose bioinks supported cell proliferation in 3D bioprinting for tissue engineering. Additional applications in biosensors and personal care products were also identified. This study advances sustainable materials science, aligning resource conservation with circular economy principles to address biomedical sector needs. [Abstract copyright: © 2025 The Author(s). The Chemical Record published by The Chemical Society of Japan and Wiley-VCH GmbH.]
U2 - 10.1002/tcr.202400249
DO - 10.1002/tcr.202400249
M3 - Review article
C2 - 40035542
SN - 1527-8999
JO - Chemical Record
JF - Chemical Record
M1 - e202400249
ER -