This paper investigates improvement possibilities in the cleaning operations undertaken at an industrial brewery. Experiments were performed on a bench scale cleaning rig which was designed to simulate ‘real life’ cleaning conditions of a cleanin- place (CIP) set in the brewery. The rig was used to clean consistently fouled coupons using difficult soils from the brewery. The objective of the experiments was to determine the effect on cleaning performance with varied levels of Na2CO3 in the detergent and the maximum level that may be present before cleaning quality is impacted. The shear force of the cleaning fluid across the surface of the coupon was also varied to determine the impact on cleaning performance. Data collected from these offline measurements has been used to predict the end point of the detergent usage based on cost optimisation within the empirically determined limits. The results show that the NaOH detergent usage can be extended without impacting the cleaning quality and preventing premature disposal. This will provide an increased confidence level when cleaning fermenters with NaOH. It will also reduce cleaning costs and benefit the environment by reducing chemical effluent and minimising water consumption.