TY - JOUR
T1 - Pain neurophysiology education for the management of individuals with chronic low back pain
T2 - A systematic review and meta-analysis
AU - Clarke, Clare Louise
AU - Ryan, Cormac
AU - Martin, Denis J.
PY - 2011/12/1
Y1 - 2011/12/1
N2 - Pain neurophysiology education (PNE) is a form of education for patients with chronic low back pain (CLBP). The purpose of this systematic review was to investigate the evidence for PNE in the management of pateints with CLBP. A literature search of MEDLINE, CINAHL and AMED was performed from 1996(01)-2010(09). RCT appraisal and synthesis was assessed using the Cochrane Back Review Group (CBRG) guidelines. The main outcome measures were pain, physical-function, psychological-function, and social-function. Two moderate quality RCTs (n= 122) were included in the final review. According to the CBRG criteria there was very low quality evidence that PNE is beneficial for pain, physical-function, psychological-function, and social-function. Meta-analysis found PNE produced statistically significant but clinically small improvements in short-term pain of 5. mm (0, 10.0. mm) [mean difference (95%CI)] on the 100. mm VAS. This review was limited by the small number of studies (n= 2) that met the inclusion criteria and by the fact that both studies were produced by the same group that published the PNE manual. These factors contributed to the relatively low grading of the evidence. There is a need for more studies investigating PNE by different research groups to support early promising findings. Until then firm clinical recommendations cannot be made.
AB - Pain neurophysiology education (PNE) is a form of education for patients with chronic low back pain (CLBP). The purpose of this systematic review was to investigate the evidence for PNE in the management of pateints with CLBP. A literature search of MEDLINE, CINAHL and AMED was performed from 1996(01)-2010(09). RCT appraisal and synthesis was assessed using the Cochrane Back Review Group (CBRG) guidelines. The main outcome measures were pain, physical-function, psychological-function, and social-function. Two moderate quality RCTs (n= 122) were included in the final review. According to the CBRG criteria there was very low quality evidence that PNE is beneficial for pain, physical-function, psychological-function, and social-function. Meta-analysis found PNE produced statistically significant but clinically small improvements in short-term pain of 5. mm (0, 10.0. mm) [mean difference (95%CI)] on the 100. mm VAS. This review was limited by the small number of studies (n= 2) that met the inclusion criteria and by the fact that both studies were produced by the same group that published the PNE manual. These factors contributed to the relatively low grading of the evidence. There is a need for more studies investigating PNE by different research groups to support early promising findings. Until then firm clinical recommendations cannot be made.
UR - http://www.scopus.com/inward/record.url?scp=80054094090&partnerID=8YFLogxK
U2 - 10.1016/j.math.2011.05.003
DO - 10.1016/j.math.2011.05.003
M3 - Review article
C2 - 21705261
AN - SCOPUS:80054094090
SN - 1356-689X
VL - 16
SP - 544
EP - 549
JO - Manual Therapy
JF - Manual Therapy
IS - 6
ER -