Pharmaceutically versatile sulfated polysaccharide based bionano platforms

Sreejith Raveendran, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar

Research output: Contribution to journalArticlepeer-review


Sulfated polysaccharides are complex polysaccharide molecules with excellent physico-chemical properties and bioactivities. On the basis of origin, they are classified as plant, animal, microbial and chemically synthesized sulfated polysaccharides. They have been widely applied in the fields of material and biological sciences. Biocompatibility and biodegradability of these molecules facilitate their increased use in the nanoparticle synthesis and tissue engineering applications. This review focuses on the structure, function and applications of important types of natural and chemically derived sulfated polysaccharides in the fields of nanotechnology and biomedical sciences. In the first part, we discuss the classification and role of sulfated polysaccharides in various fields. Later, we elaborate the specific bionano applications of commercially important sulfated polysaccharides in ionic gelation, stabilizing, cross-linking, capping and encapsulation of drugs. Finally, we conclude with the future scope and advanced applications of sulfated polysaccharides in various fields of interdisciplinary science.

Original languageEnglish
Pages (from-to)605-626
Number of pages22
JournalNanomedicine: Nanotechnology, Biology, and Medicine
Issue number5
Early online date22 Jan 2013
Publication statusPublished - 31 Jul 2013


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