Polymer Based Microchip for Combined Capillary Electrophoresis and Electrochemical Detection

Mamun-ur Rashid, V. Auger, L. Williams, Y. Dou, S. Pruneanu, Z. Ali

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    Abstract

    We have developed Microsystems with capillary electrophoresis and an electrochemical detector (CE-ECD). The microfabricated CE-ECD systems can be used as a disposable device and the characteristics have been optimized for application in electrochemical detection. The system has been realized on a Polystyrene (PS) polymer chip with gold electrodes. The injection and separation channels were produced by relatively simple and inexpensive methods. An electro-osmotic flow system (EOF) and a three-electrode electrochemical detector were fabricated on the same substrate in a single process. Cyclic voltammetry has been used to test the electrodes behaviour with catechol and dopamine in buffers of different pH. In this article, we give an overview on the methodological aspects of coupling ED (electrochemical Detection) with Capillary Electrophoretic systems.
    Original languageEnglish
    Title of host publicationProceedings of the 29th annual international conference of the IEEE EMBS
    Pages111-114
    DOIs
    Publication statusPublished - 2007
    Event29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Lyon, France
    Duration: 23 Aug 200726 Aug 2007
    Conference number: 29

    Conference

    Conference29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    CountryFrance
    CityLyon
    Period23/08/0726/08/07

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    Rashid, M., Auger, V., Williams, L., Dou, Y., Pruneanu, S., & Ali, Z. (2007). Polymer Based Microchip for Combined Capillary Electrophoresis and Electrochemical Detection. In Proceedings of the 29th annual international conference of the IEEE EMBS (pp. 111-114) https://doi.org/10.1109/IEMBS.2007.4352235