Polymer Based Microchip for Combined Capillary Electrophoresis and Electrochemical Detection

Mamun-ur Rashid; V. Auger; L. Williams; Y. Dou; S. Pruneanu; Z. Ali

doi:10.1109/IEMBS.2007.4352235

Polymer Based Microchip for Combined Capillary Electrophoresis and Electrochemical Detection

Mamun-ur Rashid, V. Auger, L. Williams, Y. Dou, S. Pruneanu, Z. Ali

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

243 Downloads (Pure)

Abstract

We have developed Microsystems with capillary electrophoresis and an electrochemical detector (CE-ECD). The microfabricated CE-ECD systems can be used as a disposable device and the characteristics have been optimized for application in electrochemical detection. The system has been realized on a Polystyrene (PS) polymer chip with gold electrodes. The injection and separation channels were produced by relatively simple and inexpensive methods. An electro-osmotic flow system (EOF) and a three-electrode electrochemical detector were fabricated on the same substrate in a single process. Cyclic voltammetry has been used to test the electrodes behaviour with catechol and dopamine in buffers of different pH. In this article, we give an overview on the methodological aspects of coupling ED (electrochemical Detection) with Capillary Electrophoretic systems.

Original language	English
Title of host publication	Proceedings of the 29th annual international conference of the IEEE EMBS
Pages	111-114
DOIs	https://doi.org/10.1109/IEMBS.2007.4352235
Publication status	Published - 2007
Event	29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Lyon, France Duration: 23 Aug 2007 → 26 Aug 2007 Conference number: 29

Conference

Conference	29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Country/Territory	France
City	Lyon
Period	23/08/07 → 26/08/07

Bibliographical note

Author can archive publisher's version/PDF.

Access to Document

10.1109/IEMBS.2007.4352235

Full textLicence: CC BY-NC-ND

http://ieeexplore.ieee.org/document/4352235/

Cite this

@inproceedings{fac3c20c32c04c54a2d1514c150befb8,

title = "Polymer Based Microchip for Combined Capillary Electrophoresis and Electrochemical Detection",

abstract = "We have developed Microsystems with capillary electrophoresis and an electrochemical detector (CE-ECD). The microfabricated CE-ECD systems can be used as a disposable device and the characteristics have been optimized for application in electrochemical detection. The system has been realized on a Polystyrene (PS) polymer chip with gold electrodes. The injection and separation channels were produced by relatively simple and inexpensive methods. An electro-osmotic flow system (EOF) and a three-electrode electrochemical detector were fabricated on the same substrate in a single process. Cyclic voltammetry has been used to test the electrodes behaviour with catechol and dopamine in buffers of different pH. In this article, we give an overview on the methodological aspects of coupling ED (electrochemical Detection) with Capillary Electrophoretic systems.",

author = "Mamun-ur Rashid and V. Auger and L. Williams and Y. Dou and S. Pruneanu and Z. Ali",

note = "Author can archive publisher's version/PDF. ; 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society ; Conference date: 23-08-2007 Through 26-08-2007",

year = "2007",

doi = "10.1109/IEMBS.2007.4352235",

language = "English",

isbn = "9781424407880",

pages = "111--114",

booktitle = "Proceedings of the 29th annual international conference of the IEEE EMBS",

}

Rashid, M, Auger, V, Williams, L, Dou, Y, Pruneanu, S & Ali, Z 2007, Polymer Based Microchip for Combined Capillary Electrophoresis and Electrochemical Detection. in Proceedings of the 29th annual international conference of the IEEE EMBS. pp. 111-114, 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Lyon, France, 23/08/07. https://doi.org/10.1109/IEMBS.2007.4352235

TY - GEN

T1 - Polymer Based Microchip for Combined Capillary Electrophoresis and Electrochemical Detection

AU - Rashid, Mamun-ur

AU - Auger, V.

AU - Williams, L.

AU - Dou, Y.

AU - Pruneanu, S.

AU - Ali, Z.

N1 - Conference code: 29

PY - 2007

Y1 - 2007

N2 - We have developed Microsystems with capillary electrophoresis and an electrochemical detector (CE-ECD). The microfabricated CE-ECD systems can be used as a disposable device and the characteristics have been optimized for application in electrochemical detection. The system has been realized on a Polystyrene (PS) polymer chip with gold electrodes. The injection and separation channels were produced by relatively simple and inexpensive methods. An electro-osmotic flow system (EOF) and a three-electrode electrochemical detector were fabricated on the same substrate in a single process. Cyclic voltammetry has been used to test the electrodes behaviour with catechol and dopamine in buffers of different pH. In this article, we give an overview on the methodological aspects of coupling ED (electrochemical Detection) with Capillary Electrophoretic systems.

AB - We have developed Microsystems with capillary electrophoresis and an electrochemical detector (CE-ECD). The microfabricated CE-ECD systems can be used as a disposable device and the characteristics have been optimized for application in electrochemical detection. The system has been realized on a Polystyrene (PS) polymer chip with gold electrodes. The injection and separation channels were produced by relatively simple and inexpensive methods. An electro-osmotic flow system (EOF) and a three-electrode electrochemical detector were fabricated on the same substrate in a single process. Cyclic voltammetry has been used to test the electrodes behaviour with catechol and dopamine in buffers of different pH. In this article, we give an overview on the methodological aspects of coupling ED (electrochemical Detection) with Capillary Electrophoretic systems.

U2 - 10.1109/IEMBS.2007.4352235

DO - 10.1109/IEMBS.2007.4352235

M3 - Conference contribution

SN - 9781424407880

SP - 111

EP - 114

BT - Proceedings of the 29th annual international conference of the IEEE EMBS

T2 - 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Y2 - 23 August 2007 through 26 August 2007

ER -

Polymer Based Microchip for Combined Capillary Electrophoresis and Electrochemical Detection

Abstract

Conference

Bibliographical note

Access to Document

Fingerprint

Cite this