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Relationship Between Tau, β Amyloid and α-Synuclein Pathologies

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

It is becoming increasing clear that multiple pathological lesions co-exist in the brains of the demented and non-demented elderly, and with putative interactions revealed at the molecular level in addition to the cumulative effects on brain damage, mounting evidence suggests manifestation of multiple protein aggregates will have implications for the clinical course of many neurodegenerative diseases associated with dementia. In this section we will discuss how the presence of multiple pathological lesions can affect the pathological and clinical phenotype of neurodegenerative disorders.

Original languageEnglish
Title of host publicationTau Biology
EditorsAkihiko Takashima, Benjamin Wolozin, Luc Buee
PublisherSpringer
Pages169-176
Number of pages8
ISBN (Electronic)9789813293588
ISBN (Print)9789813293571, 9789813293601
DOIs
Publication statusPublished - 25 Feb 2020
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1184
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

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