Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis

Keyphrases

• Industrial Strains 100%
• Avermectin 100%
• Streptomyces Avermitilis 100%
• Biological Engineering 100%
• Overproducer 40%
• High-producing Strain 40%
• High-throughput Screening 20%
• Regulatory System 20%
• Human Health 20%
• Human Animals 20%
• Reverse Engineering 20%
• Microarray Analysis 20%
• Percentage Yield 20%
• Transcriptional Level 20%
• Regulatory Genes 20%
• Biosynthetic Genes 20%
• Actinomycetes 20%
• Conserved Regions 20%
• Avermectin Production 20%
• Mutant Library 20%
• Animal Health 20%
• Wild Strain 20%
• Promoter Region 20%
• Animal Agriculture 20%
• Transcription Level 20%
• Production Culture 20%
• Targeted Proteomics 20%
• Pathway-specific 20%
• Error-prone PCR 20%
• Overexpression 20%

Biochemistry, Genetics and Molecular Biology

• Transcription 100%
• Streptomyces avermitilis 100%
• Metabolite 50%
• Microarrays 50%
• Actinobacteria 50%
• Type Strain 50%
• High Throughput Screening 50%
• Promoter Region 50%
• Wild Type 50%
• Animal Health 50%
• Locus Control Region 50%

Immunology and Microbiology

• Streptomyces avermitilis 100%
• Actinobacteria 50%
• Metabolite 50%
• Type Strain 50%
• Promoter Region 50%
• Wild Type 50%
• High Throughput Screening 50%
• Animal Health 50%