Abstract
The saturation concentration of ibuprofen in
acrylic adhesive layers was established using microscopy,
differential scanning calorimetry (DSC) and rheometry,
21 days after preparation. DSC predicted a saturation
solubility of 14.84%w/w similar to the microscopic examination showing the presence of crystal nuclei at 14.8%w/w
after 21 days. Rheological measurements predicted a saturation concentration of between 19.5–21.5%w/w, similar
to the macroscopic appearance of the layers.
acrylic adhesive layers was established using microscopy,
differential scanning calorimetry (DSC) and rheometry,
21 days after preparation. DSC predicted a saturation
solubility of 14.84%w/w similar to the microscopic examination showing the presence of crystal nuclei at 14.8%w/w
after 21 days. Rheological measurements predicted a saturation concentration of between 19.5–21.5%w/w, similar
to the macroscopic appearance of the layers.
| Original language | English |
|---|---|
| Pages (from-to) | 1467-1468 |
| Number of pages | 2 |
| Journal | Journal of Pharmacy and Pharmacology |
| Volume | 62 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 1 Sept 2010 |
| Externally published | Yes |
| Event | Pharmaceutical Sciences Conference (PharmSci) 2010 - Manchester, United Kingdom Duration: 1 Sept 2010 → 3 Sept 2010 |