Risk factors for age-related macular disease

Emma Berrow; Hannah Bartlett; Frank Eperjesi; Jonathan M. Gibson

Risk factors for age-related macular disease

Emma Berrow
, Hannah Bartlett
, Frank Eperjesi
, Jonathan M. Gibson

Research output: Contribution to journal › Article › peer-review

Abstract

Although the pathogenesis of age-related macular disease (ARMD) is still not fully understood, genetic and environmental factors are
implicated. Epidemiological studies have found conflicting findings between ARMD development and many potential risk factors. This
review provides an up-to-date account of modifiable and non-modifiable risk factors associated with ARMD development, with potential
mechanisms between risk factors and ARMD development described. Age, smoking and genetic factors appear to be consistently
associated with an increased risk of developing ARMD. However, ageing and genetic disposition cannot be currently modified, leading to
increased interest as to how other modifiable factors may reduce the risk of ARMD.

Original language	English
Pages (from-to)	143-153
Number of pages	11
Journal	European Ophthalmic Review
Volume	5
Issue number	2
Publication status	Published - 2011
Externally published	Yes

Cite this

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title = "Risk factors for age-related macular disease",

abstract = "Although the pathogenesis of age-related macular disease (ARMD) is still not fully understood, genetic and environmental factors are implicated. Epidemiological studies have found conflicting findings between ARMD development and many potential risk factors. This review provides an up-to-date account of modifiable and non-modifiable risk factors associated with ARMD development, with potential mechanisms between risk factors and ARMD development described. Age, smoking and genetic factors appear to be consistently associated with an increased risk of developing ARMD. However, ageing and genetic disposition cannot be currently modified, leading to increased interest as to how other modifiable factors may reduce the risk of ARMD.",

author = "Emma Berrow and Hannah Bartlett and Frank Eperjesi and Gibson, \{Jonathan M.\}",

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AU - Bartlett, Hannah

AU - Eperjesi, Frank

AU - Gibson, Jonathan M.

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N2 - Although the pathogenesis of age-related macular disease (ARMD) is still not fully understood, genetic and environmental factors are implicated. Epidemiological studies have found conflicting findings between ARMD development and many potential risk factors. This review provides an up-to-date account of modifiable and non-modifiable risk factors associated with ARMD development, with potential mechanisms between risk factors and ARMD development described. Age, smoking and genetic factors appear to be consistently associated with an increased risk of developing ARMD. However, ageing and genetic disposition cannot be currently modified, leading to increased interest as to how other modifiable factors may reduce the risk of ARMD.

AB - Although the pathogenesis of age-related macular disease (ARMD) is still not fully understood, genetic and environmental factors are implicated. Epidemiological studies have found conflicting findings between ARMD development and many potential risk factors. This review provides an up-to-date account of modifiable and non-modifiable risk factors associated with ARMD development, with potential mechanisms between risk factors and ARMD development described. Age, smoking and genetic factors appear to be consistently associated with an increased risk of developing ARMD. However, ageing and genetic disposition cannot be currently modified, leading to increased interest as to how other modifiable factors may reduce the risk of ARMD.

UR - https://research.aston.ac.uk/en/publications/8e8de884-f452-4999-ac24-4943adfb53ef

M3 - Article

VL - 5

SP - 143

EP - 153

JO - European Ophthalmic Review

JF - European Ophthalmic Review

IS - 2

ER -

Risk factors for age-related macular disease

Abstract

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