Sequential Analysis of Drug Encapsulated Nanoparticle Transport and Drug Release Using Multicore Shared-memory Environment

Norma Alias, Md. Rajibul Islam, Tahir Ahmad, Mohammad Abdur Razzaque

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Mathematical modelling of drug delivery is a field of progressively rising industrial and academic significance with a vast future potential due to the remarkable progresses in information technology. The drug encapsulated nanoparticle transport simulation using multicore computing can be expected to notably enhance in precision and acceptance of application. Computer simulations are likely to become an essential component of upcoming research and improvement in pharmaceutical technology, equivalent to other scientific disciplines. Mathematical algorithms and programs can be projected to be consistently utilized to assist enhancing the design of novel dosage forms of drug delivery and release. A pragmatic mathematical model is anchored in equations that portray actual phenomena like dissolution, mass transport by diffusion, viscosity, velocity, transition, etc. The partial differential equations involved can be solved provided initial and boundary conditions are known. Analytical solutions can be obtained for simple cases. This study provides an outline on the modern state of the art of mathematical modelling of drug transport and release models. Sequential algorithms for the drug delivery and drug release will be implemented on multicore shared-memory environment. Preferably, the design parameters’ effects of the nanoparticle transport form on the resultant drug concentration time profiles at the site of action and the pharmacodynamic effects will become knowable.
Original languageEnglish
Title of host publicationFourth International Conference and Workshops on Basic and Applied Sciences (4th ICOWOBAS) and Regional Annual Fundamental Science Symposium 2013 (11th RAFSS)
Pages1-6
Number of pages6
Publication statusPublished - 3 Sep 2013

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