Abstract
Mass spectrometry-mass spectrometry (MS-MS) techniques have been used in qualitative structural studies and have shown significant advantages over current methods in the areas of impurity identification, background reduction using soft ionisation techniques and extraction of fragmentation information from complex mixtures. Direct MS-MS and gas chromatography-MS-MS have also been employed in the quantitative analysis of know compounds in complex mixtures. The enhanced selectivity and speed of method development are particularly impressive features. The work has been carried out using a Finnigan MAT TSQ triple quadrupole and VG Analytical 7070EQ hybrid instrument.
Original language | English |
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Pages (from-to) | 167-177 |
Number of pages | 11 |
Journal | Journal of Chromatography A |
Volume | 328 |
Issue number | C |
DOIs | |
Publication status | Published - 1 Jan 1985 |