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Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction

  • Gianni Chessari
  • , Ian R. Hardcastle
  • , Jong Sook Ahn
  • , Burcu Anil
  • , Elizabeth Anscombe
  • , Ruth H. Bawn
  • , Luke D. Bevan
  • , Timothy J. Blackburn
  • , Ildiko Buck
  • , Celine Cano
  • , Benoit Carbain
  • , Juan Castro
  • , Ben Cons
  • , Sarah J. Cully
  • , Jane A. Endicott
  • , Lynsey Fazal
  • , Bernard T. Golding
  • , Roger J. Griffin
  • , Karen Haggerty
  • , Suzannah J. Harnor
  • Keisha Hearn, Stephen Hobson, Rhian S. Holvey, Steven Howard, Claire E. Jennings, Christopher N. Johnson, John Lunec, Duncan C. Miller, David R. Newell, Martin E. M. Noble, Judith Reeks, Charlotte H. Revill, Christiane Riedinger, Jeffrey D. St. Denis, Emiliano Tamanini, Huw Thomas, Neil T. Thompson, Mladen Vinković, Stephen R. Wedge, Pamela A. Williams, Nicola E. Wilsher, Bian Zhang, Yan Zhao

Research output: Contribution to journalArticlepeer-review

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science