Abstract
Candida tropicalis strain Fl0-1 and its recombinant strain CZ-15 can be used for 1,11-dicarboxylic acid (DCA13) production, and in CZ-15, one copy of carnitine acetyltransferase(CAT) genes is disrupted. The sucrose-added fed-batch fermentation of F10-1 and CZ-15 was studied. The results showed that the optimal feeding time and the optimal sucrose concentration were different for F10-1 and CZ-15. By feeding sucrose in the acid production stage, for F10-1 and CZ-15, the acid production was increased by 25.0% and 23.4%, reaching 99.5 and 108.1 g / L, and the alkane conversion rate was increased by 35.5% and 28.6%, respectively.
| Original language | Chinese (Simplified) |
|---|---|
| Pages (from-to) | 814-817 |
| Number of pages | 4 |
| Journal | Guocheng Gongcheng Xuebao/The Chinese Journal of Process Engineering |
| Volume | 6 |
| Issue number | 5 |
| Publication status | Published - 1 Oct 2006 |