The ergogenic effect of long-term use of high dose salbutamol

John Dickinson, John Molphy, Neil Chester, Mike Loosemore, Greg Whyte

Research output: Contribution to journalArticlepeer-review

Abstract

Objective:
Investigate the effect of inhaling 1600 μg salbutamol for 6 weeks on endurance, strength, and power performances.

Design:
Randomized double-blind, mixed-model repeated measures.

Participants:
Sixteen male athletes (mean ± SD: age, 20.1 ± 1.6 years; height, 179.9 ± 8.2 cm; weight, 74.6 ± 9.1 kg).

Interventions:
Participants were assigned to either a placebo inhaler (PLA) or inhaled 1600 μg salbutamol group (SAL). Over 6 weeks, participants inhaled PLA or SAL and completed 4 training sessions per week that focused on endurance, strength, and power.

Main Outcome Measures:
Participants completed the assessments of peak oxygen consumption (



), 3-km time trial, vertical jump height, 1 repetition maximum (1RM) bench and leg press, and peak torque knee flexion and extension. Assessments were undertaken at baseline, week 3, and week 6.

Results:
Over the 6 weeks, PLA and SAL groups improved



(51.7 ± 4.7 vs 56.8 ± 7.1 mL·min−1·kg−1; 53.1 ± 6.1 vs 55.0 ± 6.7 mL·min−1·kg−1); 3-km running time trial (988.6 ± 194.6 vs 947.5 ± 155.5 seconds; 1040.4 ± 187.4 vs 1004.2 ± 199.4 seconds); 1RM bench press (65.7 ± 15.4 vs 70.3 ± 13.8 kg; 64.3 ± 14.0 vs 72.5 ± 15.3 kg); and leg press (250.0 ± 76.4 vs 282.5 ± 63.6 kg; 217.9 ± 54.0 vs 282.8 ± 51.9 kg). The SAL group did not improve significantly greater in any endurance or strength and power measure when compared with the PLA group.

Conclusions:
Inhaling 1600 µg salbutamol daily over 6 weeks does not result in significant improvements in endurance, or strength and power performances.
Original languageEnglish
Pages (from-to)474-481
JournalClinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
Volume24
Issue number6
DOIs
Publication statusPublished - 1 Nov 2014
Externally publishedYes

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