TY - JOUR
T1 - The mechanism of decomposition of N-methyl-N-nitrosourea in aqueous solution according to 13C and 15N NMR studies
T2 - Quantitative fragmentation to cyanate
AU - Bleasdale, Christine
AU - Golding, Bernard T.
AU - McGinnis, Joseph
AU - Müller, Susanna
AU - Watson, William P.
PY - 1991/12/1
Y1 - 1991/12/1
N2 - The use of 13C NMR spectroscopy to monitor the decomposition of [13CO]N-methyl-N-nitrosourea, and of 15N NMR spectroscopy to follow the decomposition of [15NH2]N-methyl-N- nitrosourea, both in aqueous phosphate buffer at pH 7, shows the initial product to be cyanate rather than carbamate; the cyanate reacts with phosphate to give carbamoyl phosphate.
AB - The use of 13C NMR spectroscopy to monitor the decomposition of [13CO]N-methyl-N-nitrosourea, and of 15N NMR spectroscopy to follow the decomposition of [15NH2]N-methyl-N- nitrosourea, both in aqueous phosphate buffer at pH 7, shows the initial product to be cyanate rather than carbamate; the cyanate reacts with phosphate to give carbamoyl phosphate.
UR - http://www.scopus.com/inward/record.url?scp=0026327993&partnerID=8YFLogxK
U2 - 10.1039/C39910001726
DO - 10.1039/C39910001726
M3 - Article
AN - SCOPUS:0026327993
SN - 0022-4936
SP - 1726
EP - 1728
JO - Journal of the Chemical Society, Chemical Communications
JF - Journal of the Chemical Society, Chemical Communications
IS - 24
ER -