Time-frequency domain prior constrained deep unfolding network for low-dose CT reconstruction

  • Xiong Zhang
  • , Xinbo Zhang
  • , Xinzhong Li
  • , Zulfiqur Ali
  • , Yue Wang
  • , Hong Shangguan
  • , Xueying Cui

Research output: Contribution to journalArticlepeer-review

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Abstract

Background:
Low-dose computed tomography (LDCT) effectively reduces the risk of malignant disease; however, reducing the radiation dose introduces additional noise and stripe artifacts in the CT imaging process. While Convolutional Neural Networks (CNN) have demonstrated performance advantages in LDCT imaging tasks, their end-to-end network architecture limits adaptability to CT reconstruction tasks, leaving room for further performance improvement.
Objective:
To propose a low-dose CT reconstruction network based on the iterative algorithms, incorporating an interpretable network architecture to achieve superior reconstruction performance.
Methods:
To better adapt to CT reconstruction tasks, we proposed an interpretable deep unfolding network leveraging time-frequency and image domain priors to fully exploit the features extracted in the transform domain. The iterative optimization process of the proposed algorithm is mapped into a deep unfolding network, and a Stage Information Memory Network (SIMN) is designed to address information loss between adjacent stages and within each stage.
Results:
Experimental results on Mayo and Piglet datasets show that the proposed model outperforms state-of-the-art techniques in both quantitative metrics and visual quality.
Conclusions:
The proposed network effectively removes artifacts and noise from low-dose CT images, achieving excellent reconstruction performance.
Original languageEnglish
Pages (from-to)819-830
Number of pages12
JournalJournal of X-Ray Science and Technology
Volume33
Issue number5
DOIs
Publication statusPublished - 24 Sept 2025

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