Abstract
A transdermal patch is provided, wherein the patch comprises a cross-linked poly(ethylene oxide) hydrogel loaded with naltrexone, or a pharmaceutically acceptable salt or solvate thereof, and an occlusive adhesive tape. The poly(ethylene oxide) hydrogel has a crosslink density of at least 4.5×10−4 mol cm−3 and not more than 16×10−4 mol cm−3. Also provided are methods for preparing naltrexone-loaded cross-linked poly(ethylene oxide) hydrogels, transdermal patches for use as a medicament, for example in the treatment of a specified condition with LDN therapy.
| Original language | English |
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| Patent number | US2022387342 |
| IPC | A61K 47/ 10 A I |
| Priority date | 22/10/20 |
| Publication status | Published - 8 Dec 2022 |