Abstract
Abstract
Objectives
This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows:
To assess the diagnostic accuracy of endometrial sampling with histology in the diagnosis of endometrial cancer in women with postmenopausal bleeding and thickened endometrium on ultrasound. Diagnosis will be verified by the reference standards, hysteroscopy with histology, obtained by targeted (such as grasp biopsy of the endometrium or resection of focal pathology) or global sampling (with dilation and curettage), and histology of hysterectomy specimens.
Secondary objectives
To determine the diagnostic accuracy of different sampling devices and methods in the detection of endometrial cancer
To assess the diagnostic accuracy of endometrial sampling devices and methods to detect endometrial hyperplasia
To determine accuracy in diagnosing endometrial cancer and endometrial hyperplasia at different endometrial thicknesses of 3 mm, 4 mm and 5 mm
To investigate sources of heterogeneity
Objectives
This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows:
To assess the diagnostic accuracy of endometrial sampling with histology in the diagnosis of endometrial cancer in women with postmenopausal bleeding and thickened endometrium on ultrasound. Diagnosis will be verified by the reference standards, hysteroscopy with histology, obtained by targeted (such as grasp biopsy of the endometrium or resection of focal pathology) or global sampling (with dilation and curettage), and histology of hysterectomy specimens.
Secondary objectives
To determine the diagnostic accuracy of different sampling devices and methods in the detection of endometrial cancer
To assess the diagnostic accuracy of endometrial sampling devices and methods to detect endometrial hyperplasia
To determine accuracy in diagnosing endometrial cancer and endometrial hyperplasia at different endometrial thicknesses of 3 mm, 4 mm and 5 mm
To investigate sources of heterogeneity
| Original language | English |
|---|---|
| Journal | The Cochrane database of systematic reviews |
| Publication status | Published - 20 Jun 2024 |