Understanding the physical properties, toxicities and anti-microbial activities of choline-amino acid-based salts

Low-toxic variants of ionic liquids

Amandin Foulet, Ouahid Be Ghanem, Mohanad El-Harbawi, Jean-Marc Lévêque, Mohamed Ibrahim Abdul Mutalib, Chun Yang Yin

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    Abstract

    Ionic liquids (ILs) are often touted as potential 'green' substitutes for volatile organic compounds in process chemistry. However, their often high solubility in water limits their applications since discharge of spent ILs into natural water bodies may have significant detrimental eco-toxicological consequences for aquatic organisms. This is especially true for most imidazolium and pyrdinium based ILs which have been proven as toxic to aquatic life organisms. The challenge is therefore to synthesize ILs which exhibit inherently low aquatic toxicity. In the present work, five choline based ILs pairing five different amino acid anions [Cho][AA] have been synthesized and characterized. Their thermal stability, density, viscosity and thermal expansion coefficient were reported. The toxicity behavior of a synthesized ILs were investigated on guppy fish (Poecilia reticulate) and three microbial species. Fish acute toxicity test reveal that the studied ILs could be classified as non-toxic while their 50% effective concentrations (EC50) were found to be comparable to the least toxic imidazolium-based ILs. © 2016 Elsevier B.V. All rights reserved.
    Original languageEnglish
    Pages (from-to)133-138
    JournalJournal of Molecular Liquids
    Volume221
    Early online date25 May 2016
    DOIs
    Publication statusPublished - Sep 2016

    Fingerprint

    Ionic Liquids
    choline
    Poisons
    Choline
    Ionic liquids
    toxicity
    amino acids
    Toxicity
    Amino acids
    Physical properties
    Salts
    physical properties
    salts
    Amino Acids
    liquids
    fishes
    organisms
    Fish
    expansion
    Aquatic organisms

    Cite this

    Foulet, Amandin ; Ghanem, Ouahid Be ; El-Harbawi, Mohanad ; Lévêque, Jean-Marc ; Mutalib, Mohamed Ibrahim Abdul ; Yin, Chun Yang. / Understanding the physical properties, toxicities and anti-microbial activities of choline-amino acid-based salts : Low-toxic variants of ionic liquids. In: Journal of Molecular Liquids. 2016 ; Vol. 221. pp. 133-138.
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    title = "Understanding the physical properties, toxicities and anti-microbial activities of choline-amino acid-based salts: Low-toxic variants of ionic liquids",
    abstract = "Ionic liquids (ILs) are often touted as potential 'green' substitutes for volatile organic compounds in process chemistry. However, their often high solubility in water limits their applications since discharge of spent ILs into natural water bodies may have significant detrimental eco-toxicological consequences for aquatic organisms. This is especially true for most imidazolium and pyrdinium based ILs which have been proven as toxic to aquatic life organisms. The challenge is therefore to synthesize ILs which exhibit inherently low aquatic toxicity. In the present work, five choline based ILs pairing five different amino acid anions [Cho][AA] have been synthesized and characterized. Their thermal stability, density, viscosity and thermal expansion coefficient were reported. The toxicity behavior of a synthesized ILs were investigated on guppy fish (Poecilia reticulate) and three microbial species. Fish acute toxicity test reveal that the studied ILs could be classified as non-toxic while their 50{\%} effective concentrations (EC50) were found to be comparable to the least toxic imidazolium-based ILs. {\circledC} 2016 Elsevier B.V. All rights reserved.",
    author = "Amandin Foulet and Ghanem, {Ouahid Be} and Mohanad El-Harbawi and Jean-Marc L{\'e}v{\^e}que and Mutalib, {Mohamed Ibrahim Abdul} and Yin, {Chun Yang}",
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    Understanding the physical properties, toxicities and anti-microbial activities of choline-amino acid-based salts : Low-toxic variants of ionic liquids. / Foulet, Amandin; Ghanem, Ouahid Be; El-Harbawi, Mohanad; Lévêque, Jean-Marc; Mutalib, Mohamed Ibrahim Abdul; Yin, Chun Yang.

    In: Journal of Molecular Liquids, Vol. 221, 09.2016, p. 133-138.

    Research output: Contribution to journalArticleResearchpeer-review

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    T1 - Understanding the physical properties, toxicities and anti-microbial activities of choline-amino acid-based salts

    T2 - Low-toxic variants of ionic liquids

    AU - Foulet, Amandin

    AU - Ghanem, Ouahid Be

    AU - El-Harbawi, Mohanad

    AU - Lévêque, Jean-Marc

    AU - Mutalib, Mohamed Ibrahim Abdul

    AU - Yin, Chun Yang

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    N2 - Ionic liquids (ILs) are often touted as potential 'green' substitutes for volatile organic compounds in process chemistry. However, their often high solubility in water limits their applications since discharge of spent ILs into natural water bodies may have significant detrimental eco-toxicological consequences for aquatic organisms. This is especially true for most imidazolium and pyrdinium based ILs which have been proven as toxic to aquatic life organisms. The challenge is therefore to synthesize ILs which exhibit inherently low aquatic toxicity. In the present work, five choline based ILs pairing five different amino acid anions [Cho][AA] have been synthesized and characterized. Their thermal stability, density, viscosity and thermal expansion coefficient were reported. The toxicity behavior of a synthesized ILs were investigated on guppy fish (Poecilia reticulate) and three microbial species. Fish acute toxicity test reveal that the studied ILs could be classified as non-toxic while their 50% effective concentrations (EC50) were found to be comparable to the least toxic imidazolium-based ILs. © 2016 Elsevier B.V. All rights reserved.

    AB - Ionic liquids (ILs) are often touted as potential 'green' substitutes for volatile organic compounds in process chemistry. However, their often high solubility in water limits their applications since discharge of spent ILs into natural water bodies may have significant detrimental eco-toxicological consequences for aquatic organisms. This is especially true for most imidazolium and pyrdinium based ILs which have been proven as toxic to aquatic life organisms. The challenge is therefore to synthesize ILs which exhibit inherently low aquatic toxicity. In the present work, five choline based ILs pairing five different amino acid anions [Cho][AA] have been synthesized and characterized. Their thermal stability, density, viscosity and thermal expansion coefficient were reported. The toxicity behavior of a synthesized ILs were investigated on guppy fish (Poecilia reticulate) and three microbial species. Fish acute toxicity test reveal that the studied ILs could be classified as non-toxic while their 50% effective concentrations (EC50) were found to be comparable to the least toxic imidazolium-based ILs. © 2016 Elsevier B.V. All rights reserved.

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